Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50011408
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106236((3R,4S)-Ethanesulfonic acid (6-benzyloxy-3-hydroxy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50099582((3R,4S)N-[3-Hydroxy-2,2-dimethyl-6-(4,4,4-trifluor...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106233(CHEMBL124308 | N-(6-Benzyloxy-3-hydroxy-2,2-dimeth...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106231(CHEMBL340910 | N-[3-Hydroxy-2,2-dimethyl-6-(4,4,4-...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106232(CHEMBL125307 | N-(6-Butoxy-3-hydroxy-2,2-dimethyl-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106237((3S,4R)-Ethanesulfonic acid (6-benzyloxy-3-hydroxy...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106234((3S,4R)-(+)-N-[3-Hydroxy-2,2-dimethyl-6-(4,4,4-tri...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106228((3R,4S)-Ethanesulfonic acid (6-fluoro-3-hydroxy-2,...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106235(CHEMBL124810 | N-(3-Hydroxy-2,2-dimethyl-6-propoxy...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106226(CHEMBL338171 | N-(6-Chloro-3-hydroxy-2,2-dimethyl-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106229(CHEMBL127435 | Ethanesulfonic acid (6-fluoro-3-hyd...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106223((3S,4R)-Ethanesulfonic acid (6-fluoro-3-hydroxy-2,...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106224(CHEMBL125259 | Ethanesulfonic acid (3-hydroxy-2,2-...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106227((3R,4S)-Ethanesulfonic acid (6-cyano-3-hydroxy-2,2...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50099567((3S,4R)-Ethanesulfonic acid (6-cyano-3-hydroxy-2,2...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106230(CHEMBL338273 | Ethanesulfonic acid (6-cyano-3-hydr...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50099567((3S,4R)-Ethanesulfonic acid (6-cyano-3-hydroxy-2,2...)
Affinity DataIC50:  4.45E+4nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50106225(Butane-1-sulfonic acid (6-cyano-3-hydroxy-2,2-dime...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed