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Found 12 Enz. Inhib. hit(s) with all data for entry = 50036984
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107130((Z)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazo...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against Bcl-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107123(5,10-Dioxy-2-phenyl-benzo[g]pteridin-4-ylamine | C...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro inhibitory activity against Bak-Bh3 peptide binding to the Bcl-2 using human myeloid leukemia cell line HL-60More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107132((2R,3S,6S,7R,8R)-8-butyl-3-(3-formamido-2-hydroxyb...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against Bcl-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107128(5-Chloro-N-[2-chloro-5-(4-chloro-benzenesulfonyl)-...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory activity against Bcl-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107124(2,9-Dimethoxy-11,12-dihydro-dibenzo[c,g][1,2]diazo...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against Bcl-2 using bromide assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107126(4-(2-Hydroxy-9H-carbazol-1-ylazo)-benzamidine, HCl...)
Affinity DataIC50:  5.80E+3nMAssay Description:In vitro inhibitory activity against Bak-Bh3 peptide binding to the Bcl-2 using human myeloid leukemia cell line HL-60More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107127(3,12-dibromo-5,10-dihydroanthra[9,1,2-cde]benzo[rs...)
Affinity DataIC50:  7.70E+3nMAssay Description:In vitro inhibitory activity against Bak-Bh3 peptide binding to the Bcl-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107131(2-Amino-6-bromo-4-(cyano-ethoxycarbonyl-methyl)-ch...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibitory activity against Bcl-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107124(2,9-Dimethoxy-11,12-dihydro-dibenzo[c,g][1,2]diazo...)
Affinity DataIC50:  1.04E+4nMAssay Description:In vitro inhibitory activity against Bak-Bh3 peptide binding to the Bcl-2 using human myeloid leukemia cell line HL-60More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107129(7-Methoxy-9-oxo-4a,9,9a,10-tetrahydro-acridine-2-d...)
Affinity DataIC50:  1.04E+4nMAssay Description:In vitro inhibitory activity against Bak-Bh3 peptide binding to the Bcl-2 using human myeloid leukemia cell line HL-60More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107125(2-bromo-1-[6-(2-bromo-1-pyridiniumyl)-2-naphthyl]p...)
Affinity DataIC50:  1.17E+4nMAssay Description:In vitro inhibitory activity against Bak-Bh3 peptide binding to the Bcl-2 using human myeloid leukemia cell line HL-60More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50107133(4-(7-oxo-7H-benzo[de]benzo[4,5]imidazo[2,1-a]isoqu...)
Affinity DataIC50:  1.40E+4nMAssay Description:In vitro inhibitory activity against Bak-Bh3 peptide binding to the Bcl-2 using human myeloid leukemia cell line HL-60More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed