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Found 45 Enz. Inhib. hit(s) with all data for entry = 50011535
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107639(3-{2-[2-(4-Chloro-2-fluoro-benzoylamino)-3-m-tolyl...)
Affinity DataIC50:  2nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107633(3-[2-Cyano-2-(2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50:  5nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107633(3-[2-Cyano-2-(2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50:  5nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107646(3-[4-Cyano-4-(2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50:  5.60nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107623(CHEMBL140756 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  6nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin L (cat L) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107626(3-{(R)-2-Cyano-2-[(S)-2-(2,4-difluoro-benzoylamino...)
Affinity DataIC50:  6.80nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107620(3-[2-(2-Benzoylamino-3-m-tolyl-propionylamino)-2-c...)
Affinity DataIC50:  9.40nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107638(CHEMBL336436 | N-(Benzyloxymethyl-cyano-methyl)-2-...)
Affinity DataIC50:  10.2nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107650(CHEMBL138661 | N-Cyanomethyl-3-(3,5-dimethyl-pheny...)
Affinity DataIC50:  11.9nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107647(CHEMBL140506 | N-{1-[(Benzyloxymethyl-cyano-methyl...)
Affinity DataIC50:  16.9nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107630(3-[4-Cyano-4-(2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50:  18nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107633(3-[2-Cyano-2-(2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50:  20nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin L (cat L) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107628(CHEMBL343423 | N-[Cyano-(3-hydroxymethyl-benzyloxy...)
Affinity DataIC50:  29nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107621(4-[2-Cyano-2-(2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50:  30.7nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107622(CHEMBL342145 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  31nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin L (cat L) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107625(3,4-Dichloro-N-[1-(cyanomethyl-carbamoyl)-2-m-toly...)
Affinity DataIC50:  31.3nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107629(3-[2-Cyano-2-(2-pentanoylamino-3-m-tolyl-propionyl...)
Affinity DataIC50:  35.7nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107634(CHEMBL140606 | N-{1-[(Benzyloxymethyl-cyano-methyl...)
Affinity DataIC50:  42nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107633(3-[2-Cyano-2-(2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50:  46nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin S (cat S) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107631(3-[2-Cyano-2-(2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50:  47nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107622(CHEMBL342145 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  48nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin S (cat S) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107641(4-Chloro-N-[1-(cyanomethyl-carbamoyl)-2-m-tolyl-et...)
Affinity DataIC50:  72nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107623(CHEMBL140756 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  87nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107623(CHEMBL140756 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  87nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107623(CHEMBL140756 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  88nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin S (cat S) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107644(3-{4-Cyano-4-[2-(2,4-difluoro-benzoylamino)-3-m-to...)
Affinity DataIC50:  110nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107627(CHEMBL139132 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  121nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107636(3-(3-Chloro-phenyl)-N-cyanomethyl-2-diphenylacetyl...)
Affinity DataIC50:  130nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107632(CHEMBL423923 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  136nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107649(3-[3-Cyano-3-(2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50:  138nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107635(CHEMBL140794 | N-Cyanomethyl-3-phenyl-2-phenylacet...)
Affinity DataIC50:  170nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin L (cat L) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107635(CHEMBL140794 | N-Cyanomethyl-3-phenyl-2-phenylacet...)
Affinity DataIC50:  226nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin S (cat S) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107637(4-Chloro-N-[1-(cyanomethyl-carbamoyl)-2-m-tolyl-et...)
Affinity DataIC50:  308nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107648(3-(3-Aminomethyl-5-methyl-phenyl)-N-cyanomethyl-2-...)
Affinity DataIC50:  358nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107622(CHEMBL342145 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  496nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107626(3-{(R)-2-Cyano-2-[(S)-2-(2,4-difluoro-benzoylamino...)
Affinity DataIC50:  554nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin L (cat L) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107643(CHEMBL140824 | N-[1-(Cyanomethyl-carbamoyl)-2-m-to...)
Affinity DataIC50:  591nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107640(CHEMBL345081 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50:  652nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107626(3-{(R)-2-Cyano-2-[(S)-2-(2,4-difluoro-benzoylamino...)
Affinity DataIC50:  937nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin S (cat S) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107624(3-(3-Carbamimidoyl-phenyl)-N-cyanomethyl-2-dipheny...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107619(CHEMBL337111 | N-Cyanomethyl-2-diphenylacetylamino...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107645(CHEMBL138586 | N-[1-(Cyanomethyl-carbamoyl)-2-m-to...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107642(CHEMBL440347 | Pentanoic acid [1-(cyanomethyl-carb...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107635(CHEMBL140794 | N-Cyanomethyl-3-phenyl-2-phenylacet...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM20096(CHEMBL344174 | benzyl N-[(1S)-1-[(cyanomethyl)carb...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed