Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 50011575
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108204(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-be...)
Affinity DataIC50:  0.550nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108202((S)-2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108192(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-4-methyl-b...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108194(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-4-sulf...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108187(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  2.30nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108185(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-benzenesul...)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108193(2-[2-Benzo[1,3]dioxol-5-yl-2-(6-carbamoyl-1-methyl...)
Affinity DataIC50:  3.10nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108196(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108191(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesul...)
Affinity DataIC50:  5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108203(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-2-sulf...)
Affinity DataIC50:  5.20nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108195(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(4-trifluoromet...)
Affinity DataIC50:  6.5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108200(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-chloro-benzenesulf...)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108197(3-(2-Benzenesulfonylamino-1-benzo[1,3]dioxol-5-yl-...)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108202((S)-2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-...)
Affinity DataIC50:  16nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108188(CHEMBL279947 | N-[2-Benzo[1,3]dioxol-5-yl-2-(6-hyd...)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50451439(CHEMBL2114305)
Affinity DataIC50:  22nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108198(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  30nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108190(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  31nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108207(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  32nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108187(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  34nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108205(CHEMBL281378 | N-{2-Benzo[1,3]dioxol-5-yl-2-[1-met...)
Affinity DataIC50:  35nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108199(CHEMBL279703 | N-[2-(6-Aminomethyl-1-methyl-1H-ind...)
Affinity DataIC50:  38nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108201(CHEMBL274758 | N-[2-Benzo[1,3]dioxol-5-yl-2-(6-cya...)
Affinity DataIC50:  61nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108196(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  68nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108189(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  72nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108185(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-benzenesul...)
Affinity DataIC50:  94nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108206(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  100nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108199(CHEMBL279703 | N-[2-(6-Aminomethyl-1-methyl-1H-ind...)
Affinity DataIC50:  204nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108198(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  210nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108186(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  210nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108195(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(4-trifluoromet...)
Affinity DataIC50:  228nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108192(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-4-methyl-b...)
Affinity DataIC50:  302nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108191(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesul...)
Affinity DataIC50:  310nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108204(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-be...)
Affinity DataIC50:  397nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108188(CHEMBL279947 | N-[2-Benzo[1,3]dioxol-5-yl-2-(6-hyd...)
Affinity DataIC50:  450nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108189(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  474nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108194(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-4-sulf...)
Affinity DataIC50:  774nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108193(2-[2-Benzo[1,3]dioxol-5-yl-2-(6-carbamoyl-1-methyl...)
Affinity DataIC50:  846nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108203(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-2-sulf...)
Affinity DataIC50:  1.06E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108200(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-chloro-benzenesulf...)
Affinity DataIC50:  1.10E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50451439(CHEMBL2114305)
Affinity DataIC50:  1.50E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108207(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataIC50:  2.20E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108197(3-(2-Benzenesulfonylamino-1-benzo[1,3]dioxol-5-yl-...)
Affinity DataIC50:  2.57E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed