Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50011577
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108215((S)-3-(2'-Cyano-biphenyl-4-yl)-2-{[(2S,3S)-1-(3,5-...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108208((S)-2-{[(2S,3S)-1-(3,5-Dichloro-benzenesulfonyl)-3...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108213((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108212((S)-2-{[(R)-3-(3,5-Dichloro-benzenesulfonyl)-thiaz...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108217((S)-2-[((S)-3-Methanesulfonyl-thiazolidine-4-carbo...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108216((S)-2-[((R)-3-Methanesulfonyl-thiazolidine-4-carbo...)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105393((S)-3-(2'-Cyano-biphenyl-4-yl)-2-{[(S)-1-(3,5-dich...)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105380((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108211((S)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108213((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108214((S)-2-{[(S)-3-(3,5-Dichloro-benzenesulfonyl)-thiaz...)
Affinity DataIC50:  6nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108210((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[((S)-thiazolid...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108217((S)-2-[((S)-3-Methanesulfonyl-thiazolidine-4-carbo...)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108209((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[((R)-thiazolid...)
Affinity DataIC50:  13nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108216((S)-2-[((R)-3-Methanesulfonyl-thiazolidine-4-carbo...)
Affinity DataIC50:  13nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108215((S)-3-(2'-Cyano-biphenyl-4-yl)-2-{[(2S,3S)-1-(3,5-...)
Affinity DataIC50:  41nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108211((S)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  50nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108208((S)-2-{[(2S,3S)-1-(3,5-Dichloro-benzenesulfonyl)-3...)
Affinity DataIC50:  53nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105393((S)-3-(2'-Cyano-biphenyl-4-yl)-2-{[(S)-1-(3,5-dich...)
Affinity DataIC50:  89nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105380((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-pyrro...)
Affinity DataIC50:  102nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108214((S)-2-{[(S)-3-(3,5-Dichloro-benzenesulfonyl)-thiaz...)
Affinity DataIC50:  160nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108210((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[((S)-thiazolid...)
Affinity DataIC50:  197nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108212((S)-2-{[(R)-3-(3,5-Dichloro-benzenesulfonyl)-thiaz...)
Affinity DataIC50:  306nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108209((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-[((R)-thiazolid...)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed