Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 50011677
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50404013(CHEMBL2112677)
Affinity DataIC50:  3.60nMAssay Description:Tested in vitro binding affinity for displacement of [3H]-M-MPEP from membrane of L(-tk) cells expressing the Metabotropic glutamate receptor 5, acti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50404013(CHEMBL2112677)
Affinity DataIC50:  10nMAssay Description:Tested in vitro binding affinity for displacement of [3H]-M-MPEP from membrane of L(-tk) cells expressing the Metabotropic glutamate receptor 5, acti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...)
Affinity DataIC50:  20nMAssay Description:In vitro for inhibitory activity of compound against recombinant Metabotropic glutamate receptor 5 evaluated as inhibition of quisqualate-stimulated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...)
Affinity DataIC50:  36nMAssay Description:In vitro for inhibitory activity of compound against recombinant Metabotropic glutamate receptor 5 evaluated as inhibition of quisqualate-stimulated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50084141((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
Affinity DataIC50:  1.10E+3nMAssay Description:Tested in vitro binding affinity for displacement of [3H]-M-MPEP from membrane of L(-tk) cells expressing the Metabotropic glutamate receptor 5, acti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50084141((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro for inhibitory activity of compound against recombinant Metabotropic glutamate receptor 5 evaluated as inhibition of quisqualate-stimulated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed