Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50011681
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM6477(4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4531(4-Phenylamino-3-quinolinecarbonitrile deriv. 1i | ...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095226(6,7-Dimethoxy-4-(4-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Dual specificity mitogen-activated protein kinase kinase (MEK-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109282(7,8-Dimethoxy-4-(4-phenoxy-phenylamino)-benzo[g]qu...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Dual specificity mitogen-activated protein kinase kinase (MEK-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109281(4-(2,4-Dichloro-phenylamino)-7,8-dimethoxy-benzo[g...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4492(4-[(2,4-Dichlorophenyl)amino]-6,7-dimethoxy-3-quin...)
Affinity DataIC50:  38nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM6477(4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...)
Affinity DataIC50:  210nMAssay Description:Inhibition of Src-transformed fibroblast cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109280(4-(3-Chloro-4-fluoro-phenylamino)-7,8-dimethoxy-be...)
Affinity DataIC50:  680nMAssay Description:Inhibition of EGFR overexpressing A431 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109280(4-(3-Chloro-4-fluoro-phenylamino)-7,8-dimethoxy-be...)
Affinity DataIC50:  680nMAssay Description:Inhibition of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4456(4-(3-Chloro-4-fluorophenylamino)-6,7-dimethoxyquin...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4531(4-Phenylamino-3-quinolinecarbonitrile deriv. 1i | ...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of EGFR overexpressing A431 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4456(4-(3-Chloro-4-fluorophenylamino)-6,7-dimethoxyquin...)
Affinity DataIC50:  5.17E+3nMAssay Description:Inhibition of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed