Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50012117
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114917((3R,5S)-5-[4-(4-Fluoro-benzyl)-5-methylsulfanyl-4H...)
Affinity DataIC50:  150nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114905((3R,5S)-5-[5-Methylsulfanyl-4-(2,3,5,6-tetrafluoro...)
Affinity DataIC50:  250nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114911((3R,5S)-1-(Naphthalene-2-sulfonyl)-5-(4-phenyl-5-p...)
Affinity DataIC50:  280nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114908((3R,5S)-5-[5-Methylsulfanyl-4-(4-trifluoromethyl-p...)
Affinity DataIC50:  360nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114915((3R,5S)-5-(5-Methylsulfanyl-4-phenyl-4H-[1,2,4]tri...)
Affinity DataIC50:  500nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114904((3R,5S)-5-(5-Cyclopropylmethylsulfanyl-4-phenyl-4H...)
Affinity DataIC50:  700nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114914((3R,5S)-5-(5-Isobutylsulfanyl-4-phenyl-4H-[1,2,4]t...)
Affinity DataIC50:  720nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114919((3R,5S)-5-(5-Methylsulfanyl-4-phenyl-4H-[1,2,4]tri...)
Affinity DataIC50:  1.20E+3nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114916((3R,5S)-5-[4-(3-Chloro-4-fluoro-phenyl)-5-methylsu...)
Affinity DataIC50:  1.20E+3nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114910((3R,5S)-1-(4-Chloro-benzenesulfonyl)-5-(5-methylsu...)
Affinity DataIC50:  1.20E+3nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114906((3R,5S)-5-(5-Methylsulfanyl-4-phenyl-4H-[1,2,4]tri...)
Affinity DataIC50:  1.30E+3nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114912((2S,4R)-4-Mercapto-2-(5-methylsulfanyl-4-phenyl-4H...)
Affinity DataIC50:  2.70E+3nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114909((3R,5S)-5-(5-Methylsulfanyl-4-phenyl-4H-[1,2,4]tri...)
Affinity DataIC50:  4.40E+3nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114907((3R,5S)-1-(4-Fluoro-benzenesulfonyl)-5-(5-methylsu...)
Affinity DataIC50:  8.95E+3nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114918((3R,5S)-1-Methanesulfonyl-5-(5-methylsulfanyl-4-ph...)
Affinity DataIC50:  1.55E+4nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114913((2S,4R)-4-Mercapto-2-(5-methylsulfanyl-4-phenyl-4H...)
Affinity DataIC50:  1.77E+4nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed