Compile Data Set for Download or QSAR
maximum 50k data
Found 45 Enz. Inhib. hit(s) with all data for entry = 50037041
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115557(4-(4-Chloro-phenyl)-piperidine-3-carboxylic acid m...)
Affinity DataKi:  7.90nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115561(4-(4-Chloro-phenyl)-3-(3-methyl-[1,2,4]oxadiazol-5...)
Affinity DataKi:  34nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115567(CHEMBL321454 | [4-(4-Chloro-phenyl)-piperidin-3-yl...)
Affinity DataKi:  69nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  108nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  155nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115555(4-(4-Chloro-phenyl)-1-methyl-3-(3-methyl-[1,2,4]ox...)
Affinity DataKi:  187nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115561(4-(4-Chloro-phenyl)-3-(3-methyl-[1,2,4]oxadiazol-5...)
Affinity DataKi:  189nMAssay Description:373 Ability to inhibit high affinity uptake of [3H]DA using rat nerve endings obtained from brain regions enriched in dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064494(CHEMBL61776 | [(S)-4-(4-Chloro-phenyl)-1-methyl-pi...)
Affinity DataKi:  198nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115567(CHEMBL321454 | [4-(4-Chloro-phenyl)-piperidin-3-yl...)
Affinity DataKi:  239nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115555(4-(4-Chloro-phenyl)-1-methyl-3-(3-methyl-[1,2,4]ox...)
Affinity DataKi:  256nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  259nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115557(4-(4-Chloro-phenyl)-piperidine-3-carboxylic acid m...)
Affinity DataKi:  279nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115560(4-(4-Chloro-phenyl)-1-(3-fluoro-propyl)-piperidine...)
Affinity DataKi:  335nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115561(4-(4-Chloro-phenyl)-3-(3-methyl-[1,2,4]oxadiazol-5...)
Affinity DataKi:  373nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115557(4-(4-Chloro-phenyl)-piperidine-3-carboxylic acid m...)
Affinity DataKi:  434nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115565(4-(4-Chloro-phenyl)-1-(3-chloro-propyl)-piperidine...)
Affinity DataKi:  441nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115566(4-(4-Chloro-phenyl)-1-(3-phenyl-propyl)-piperidine...)
Affinity DataKi:  488nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064494(CHEMBL61776 | [(S)-4-(4-Chloro-phenyl)-1-methyl-pi...)
Affinity DataKi:  497nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115566(4-(4-Chloro-phenyl)-1-(3-phenyl-propyl)-piperidine...)
Affinity DataKi:  810nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115567(CHEMBL321454 | [4-(4-Chloro-phenyl)-piperidin-3-yl...)
Affinity DataKi:  836nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115564(4-(4-Chloro-phenyl)-1-(4-hydroxy-benzyl)-piperidin...)
Affinity DataKi:  1.08E+3nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064494(CHEMBL61776 | [(S)-4-(4-Chloro-phenyl)-1-methyl-pi...)
Affinity DataKi:  1.55E+3nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115564(4-(4-Chloro-phenyl)-1-(4-hydroxy-benzyl)-piperidin...)
Affinity DataKi:  1.62E+3nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115556(4-(4-Chloro-phenyl)-1-isopropyl-piperidine-3-carbo...)
Affinity DataKi:  1.84E+3nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115563(4-(4-Chloro-phenyl)-1-(2-ethoxycarbonyl-ethyl)-pip...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115564(4-(4-Chloro-phenyl)-1-(4-hydroxy-benzyl)-piperidin...)
Affinity DataKi:  2.65E+3nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115553(4-(4-Chloro-phenyl)-1-(3,3-diphenyl-propyl)-piperi...)
Affinity DataKi:  2.69E+3nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115565(4-(4-Chloro-phenyl)-1-(3-chloro-propyl)-piperidine...)
Affinity DataKi:  3.15E+3nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115566(4-(4-Chloro-phenyl)-1-(3-phenyl-propyl)-piperidine...)
Affinity DataKi:  3.27E+3nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115556(4-(4-Chloro-phenyl)-1-isopropyl-piperidine-3-carbo...)
Affinity DataKi:  3.74E+3nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115560(4-(4-Chloro-phenyl)-1-(3-fluoro-propyl)-piperidine...)
Affinity DataKi:  4.28E+3nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115553(4-(4-Chloro-phenyl)-1-(3,3-diphenyl-propyl)-piperi...)
Affinity DataKi:  4.29E+3nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115553(4-(4-Chloro-phenyl)-1-(3,3-diphenyl-propyl)-piperi...)
Affinity DataKi:  4.34E+3nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115555(4-(4-Chloro-phenyl)-1-methyl-3-(3-methyl-[1,2,4]ox...)
Affinity DataKi:  5.96E+3nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115556(4-(4-Chloro-phenyl)-1-isopropyl-piperidine-3-carbo...)
Affinity DataKi:  6.98E+3nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115563(4-(4-Chloro-phenyl)-1-(2-ethoxycarbonyl-ethyl)-pip...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115563(4-(4-Chloro-phenyl)-1-(2-ethoxycarbonyl-ethyl)-pip...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115559(1-Acetyl-4-(4-chloro-phenyl)-piperidine-3-carboxyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115559(1-Acetyl-4-(4-chloro-phenyl)-piperidine-3-carboxyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115560(4-(4-Chloro-phenyl)-1-(3-fluoro-propyl)-piperidine...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115565(4-(4-Chloro-phenyl)-1-(3-chloro-propyl)-piperidine...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115559(1-Acetyl-4-(4-chloro-phenyl)-piperidine-3-carboxyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115558(1-Benzenesulfonyl-4-(4-chloro-phenyl)-piperidine-3...)
Affinity DataKi:  1.61E+4nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115558(1-Benzenesulfonyl-4-(4-chloro-phenyl)-piperidine-3...)
Affinity DataKi:  1.95E+4nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115558(1-Benzenesulfonyl-4-(4-chloro-phenyl)-piperidine-3...)
Affinity DataKi:  3.61E+4nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed