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Found 47 Enz. Inhib. hit(s) with all data for entry = 50012164
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115642((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Affinity DataKi:  0.160nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  0.210nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115640((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Affinity DataKi:  0.390nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115642((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Affinity DataKi:  0.550nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  0.700nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115640((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Affinity DataKi:  0.75nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Affinity DataKi:  1.40nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Affinity DataKi:  1.5nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115644((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...)
Affinity DataKi:  2nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115641((+/-)-7-2-Methyl-1,2,3,4,9,13b-hexahydro-2,4a-diaz...)
Affinity DataKi:  2nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115644((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...)
Affinity DataKi:  5.5nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115641((+/-)-7-2-Methyl-1,2,3,4,9,13b-hexahydro-2,4a-diaz...)
Affinity DataKi:  12nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115644((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...)
Affinity DataKi: >18nMAssay Description:The binding affinity of the compound at the 5-hydroxytryptamine 1A receptor determined using [3H]-5-CTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115640((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Affinity DataKi:  20nMAssay Description:The binding affinity of the compound at the Dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115644((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...)
Affinity DataKi: >20nMAssay Description:The binding affinity of the compound at the Dopamine receptor D3 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115644((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...)
Affinity DataKi: >25nMAssay Description:The binding affinity of the compound at the Dopamine receptor D4 determined using [3H]-YM-09151-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  28nMAssay Description:The binding affinity of the compound at the Dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115640((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Affinity DataKi:  47nMAssay Description:The binding affinity of the compound at the Dopamine receptor D4 determined using [3H]-YM-09151-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Affinity DataKi:  70nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 3 receptor was determined using [3H]-LY-278,584More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115640((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Affinity DataKi:  80nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 1D receptor was determined using [3H]-5-CTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  92nMAssay Description:The binding affinity of the compound at the Dopamine receptor D4 determined using [3H]-YM-09151-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115640((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Affinity DataKi:  100nMAssay Description:The binding affinity of the compound at the Dopamine receptor D3 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115642((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Affinity DataKi:  160nMAssay Description:The binding affinity of the compound at the Dopamine receptor D4 determined using [3H]-YM-09151-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115640((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Affinity DataKi:  255nMAssay Description:The binding affinity of the compound at the 5-hydroxytryptamine 1A receptor determined using [3H]-5-CTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  260nMAssay Description:The binding affinity of the compound at the Dopamine receptor D3 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115645((+/-)-8Trifluoro-methanesulfonic acid 2-methyl-1,2...)
Affinity DataKi:  277nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  345nMAssay Description:The binding affinity of the compound at the 5-hydroxytryptamine 1A receptor determined using [3H]-5-CTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115642((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Affinity DataKi:  460nMAssay Description:The binding affinity of the compound at the Dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Affinity DataKi: >500nMAssay Description:The binding affinity of the compound at the 5-hydroxytryptamine 1A receptor determined using [3H]-5-CTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115642((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Affinity DataKi:  800nMAssay Description:The binding affinity of the compound at the 5-hydroxytryptamine 1A receptor determined using [3H]-5-CTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Affinity DataKi:  1.00E+3nMAssay Description:The binding affinity of the compound at the Dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115644((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...)
Affinity DataKi:  1.46E+3nMAssay Description:The binding affinity of the compound at the Dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115642((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Affinity DataKi:  1.47E+3nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 1D receptor was determined using [3H]-5-CTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115640((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Affinity DataKi:  1.65E+3nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 3 receptor was determined using [3H]-LY-278,584More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  2.90E+3nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 3 receptor was determined using [3H]-LY-278,584More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115642((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Affinity DataKi:  3.57E+3nMAssay Description:The binding affinity of the compound at the Dopamine receptor D3 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115642((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Affinity DataKi: >5.00E+3nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 3 receptor was determined using [3H]-LY-278,584More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Affinity DataIC50:  22nMAssay Description:The binding affinity of the compound at the Norepinephrin transpoter reputake sites determined using competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115644((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...)
Affinity DataIC50: >100nMAssay Description:The binding affinity of the compound at the 5-HT reputake sites determined using competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115644((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...)
Affinity DataIC50:  260nMAssay Description:The binding affinity of the compound at the Norepinephrin transpoter reputake sites determined using competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115642((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Affinity DataIC50:  1.24E+3nMAssay Description:The binding affinity of the compound at the Norepinephrin transpoter reputake sites determined using competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115642((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Affinity DataIC50:  1.65E+3nMAssay Description:The binding affinity of the compound at the 5-HT reputake sites determined using competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataIC50:  1.78E+3nMAssay Description:The binding affinity of the compound at the Norepinephrin transpoter reputake sites determined using competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115640((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Affinity DataIC50:  2.86E+3nMAssay Description:The binding affinity of the compound at the Norepinephrin transpoter reputake sites determined using competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Affinity DataIC50:  2.90E+3nMAssay Description:The binding affinity of the compound at the 5-HT reputake sites determined using competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataIC50:  2.90E+3nMAssay Description:The binding affinity of the compound at the 5-HT reputake sites determined using competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115640((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:The binding affinity of the compound at the 5-HT reputake sites determined using competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed