Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50012198
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115967(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50:  0.600nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115966(4'-Chloro-2-(3,4,5-trimethoxy-benzoylamino)-biphen...)
Affinity DataIC50:  0.700nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50403920(CHEMBL2112212)
Affinity DataIC50:  0.800nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50403918(CHEMBL2113739)
Affinity DataIC50:  1nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115965(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50:  1nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115959(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50:  1.5nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50403916(CHEMBL2113740)
Affinity DataIC50:  2.70nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115957(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50:  3nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115969(CHEMBL305375 | N-[4-(N-Cyclohexyl-hydrazinocarbony...)
Affinity DataIC50:  3.5nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115964(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50:  4nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50403919(CHEMBL2112211)
Affinity DataIC50:  6nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115970(4'-Chloro-2-(3,4,5-trimethoxy-benzoylamino)-biphen...)
Affinity DataIC50:  9nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50403917(CHEMBL2112209)
Affinity DataIC50:  13nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50403918(CHEMBL2113739)
Affinity DataIC50:  28nMAssay Description:Binding affinity of the compound was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115970(4'-Chloro-2-(3,4,5-trimethoxy-benzoylamino)-biphen...)
Affinity DataIC50:  30nMAssay Description:Binding affinity was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinant Tachykinin rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115963(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50:  34nMAssay Description:inhibition of [3H]-Sar-SP binding to Tachykinin receptor 1 of bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50403920(CHEMBL2112212)
Affinity DataIC50:  43nMAssay Description:Binding affinity of the compound was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115957(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50:  51nMAssay Description:Binding affinity was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinant Tachykinin rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50403916(CHEMBL2113740)
Affinity DataIC50:  70nMAssay Description:Binding affinity of the compound was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115965(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50:  108nMAssay Description:Binding affinity was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinant Tachykinin rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50403917(CHEMBL2112209)
Affinity DataIC50:  162nMAssay Description:Binding affinity was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinant Tachykinin rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115963(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50:  168nMAssay Description:Binding affinity of the compound was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50403919(CHEMBL2112211)
Affinity DataIC50:  181nMAssay Description:Binding affinity of the compound was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115964(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50:  500nMAssay Description:Binding affinity was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinant Tachykinin rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115959(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50:  560nMAssay Description:Binding affinity of the compound was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115967(2-[(3,5-Bis-trifluoromethyl-benzoyl)-methyl-amino]...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinant Tachykinin rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115969(CHEMBL305375 | N-[4-(N-Cyclohexyl-hydrazinocarbony...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity of the compound was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50115966(4'-Chloro-2-(3,4,5-trimethoxy-benzoylamino)-biphen...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity was determined by measuring the inhibition of 125 I-NKA binding to transfected CHO-cells expressing human recombinant Tachykinin rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed