Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50012327
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117522((5S,6R,9S)-5-(4-Fluoro-phenyl)-9-(2-trifluoromethy...)
Affinity DataKi:  28nMAssay Description:Binding affinity of the compound to human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117508((5S,6R,9R)-5-(4-Fluoro-phenyl)-9-(2-trifluoromethy...)
Affinity DataKi:  400nMAssay Description:Binding affinity of the compound to human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117523(5-{(5S,10S)-5-(4-Fluoro-phenyl)-10-[2-methoxy-5-(5...)
Affinity DataIC50:  0.100nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117509((3S,5S,10S)-5-(4-Fluoro-phenyl)-10-[2-methoxy-5-(5...)
Affinity DataIC50:  0.100nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117515(5-[(3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(2-methoxy-p...)
Affinity DataIC50:  0.560nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117510(CHEMBL84881 | {5-[5-(4-Fluoro-phenyl)-9-(2-trifluo...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117516((3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(2-methoxy-5-tr...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117521(CHEMBL85626 | {5-[5-(4-Fluoro-phenyl)-9-(2-trifluo...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117514((3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(5-isopropyl-2-...)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117511((3S,5S,10S)-10-(5-Fluoro-2-methoxy-phenyl)-5-(4-fl...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117518((3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(2-methoxy-phen...)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117524((3S,5S,10S)-10-(2,5-Dimethoxy-phenyl)-5-(4-fluoro-...)
Affinity DataIC50:  16nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117506(5-(5,9-Diphenyl-1,7-dioxa-4-aza-spiro[5.5]undec-4-...)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117507((3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(2-trifluoromet...)
Affinity DataIC50:  24nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117513((3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(3-trifluoromet...)
Affinity DataIC50:  30nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117519((3S,5S,10S)-5-(4-Fluoro-phenyl)-10-phenyl-1,8-diox...)
Affinity DataIC50:  99nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117517(5,9-Diphenyl-1,7-dioxa-4-aza-spiro[5.5]undecane | ...)
Affinity DataIC50:  170nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117512((3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(3-methoxy-phen...)
Affinity DataIC50:  183nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50117520(5-(4-Fluoro-phenyl)-9-(3-trifluoromethyl-phenyl)-1...)
Affinity DataIC50:  513nMAssay Description:Displacement of [125I]-labeled substance P from human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed