Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 2139
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chul

LigandPNGBDBM17290(E2-adenosine hybrid compound, 8 | EM-1745 | EM1745...)
Affinity DataKi:  3nM ΔG°:  -50.6kJ/molepH: 7.5 T: 2°CAssay Description:For steady-state kinetic study of hybrid inhibitors, a Fluorolog 3 instrument was used to monitor the fluorescent signal of NADPH formed during estra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chul

LigandPNGBDBM17293(Compound 10 | MB-329-131A2 | [5-(6-amino-9H-purin-...)
Affinity DataKi:  2.50E+5nM ΔG°:  -21.4kJ/molepH: 7.5 T: 2°CAssay Description:For steady-state kinetic study of hybrid inhibitors, a Fluorolog 3 instrument was used to monitor the fluorescent signal of NADPH formed during estra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chul

LigandPNGBDBM17290(E2-adenosine hybrid compound, 8 | EM-1745 | EM1745...)
Affinity DataIC50:  52nMpH: 7.4 T: 2°CAssay Description:The enzymatic reaction was performed in the reaction buffer containing substrate, [14C]-estrone, and the test inhibitors. After the reaction, radiola...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chul

LigandPNGBDBM17288(E2-adenosine hybrid compound, 7 | [5-(6-amino-9H-p...)
Affinity DataIC50:  93nMpH: 7.4 T: 2°CAssay Description:The enzymatic reaction was performed in the reaction buffer containing substrate, [14C]-estrone, and the test inhibitors. After the reaction, radiola...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chul

LigandPNGBDBM17291(E2-adenosine hybrid compound, 9 | [5-(6-amino-9H-p...)
Affinity DataIC50:  140nMpH: 7.4 T: 2°CAssay Description:The enzymatic reaction was performed in the reaction buffer containing substrate, [14C]-estrone, and the test inhibitors. After the reaction, radiola...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chul

LigandPNGBDBM17294((13S,14S,15S)-15-methyl-13-nonyltetracyclo[8.7.0.0...)
Affinity DatapH: 7.5 T: 2°CAssay Description:For steady-state kinetic study of hybrid inhibitors, a Fluorolog 3 instrument was used to monitor the fluorescent signal of NADPH formed during estra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed