Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50037075
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  0.130nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity against the Progesterone Receptor (PR)More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity against progesterone receptor (PR) using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity against the Glucocorticoid Receptor (GR)More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118693(6-(3-Chloro-5-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50:  2.60nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118698(6-(3-Fluoro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50:  3.80nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity against the Androgen Receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118688(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  6.70nMAssay Description:Antagonist activity against the Progesterone Receptor (PR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118688(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  6.70nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118694(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118698(6-(3-Fluoro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50:  8.20nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118700(6-(3-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50:  9.30nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118695(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  9.90nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118696(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  15.1nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  15.9nMAssay Description:Antagonist activity against the Progesterone Receptor (PR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  15.9nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118695(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  17nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118697(6-(3-Methoxy-phenyl)-4,4-dimethyl-1,4-dihydro-benz...)
Affinity DataIC50:  19.5nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118689(3-Fluoro-5-(8-fluoro-4,4-dimethyl-2-oxo-1,4-dihydr...)
Affinity DataIC50:  26.2nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118700(6-(3-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118692(6-(4-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50:  37nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50:  37nMAssay Description:Antagonist activity against the Progesterone Receptor (PR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118697(6-(3-Methoxy-phenyl)-4,4-dimethyl-1,4-dihydro-benz...)
Affinity DataIC50:  38.3nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118694(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  40.2nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118694(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  40.2nMAssay Description:Antagonist activity against the Progesterone Receptor (PR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118696(5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  55nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118689(3-Fluoro-5-(8-fluoro-4,4-dimethyl-2-oxo-1,4-dihydr...)
Affinity DataIC50:  98.8nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118694(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  129nMAssay Description:Antagonist activity against the Androgen Receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50:  207nMAssay Description:Antagonist activity against the Androgen Receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118688(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  280nMAssay Description:Antagonist activity against the Androgen Receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118699(6-(2-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50:  300nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118699(6-(2-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50:  500nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118692(6-(4-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50:  642nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity against the Mineralocorticoid Receptor (MR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  1.29E+3nMAssay Description:Antagonist activity against the Androgen Receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118688(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  1.39E+3nMAssay Description:Antagonist activity against the Mineralocorticoid Receptor (MR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  1.76E+3nMAssay Description:Antagonist activity against the Glucocorticoid Receptor (GR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118688(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  1.86E+3nMAssay Description:Antagonist activity against the Glucocorticoid Receptor (GR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50:  2.37E+3nMAssay Description:Antagonist activity against the Mineralocorticoid Receptor (MR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50:  2.49E+3nMAssay Description:Antagonist activity against the Mineralocorticoid Receptor (MR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50:  2.58E+3nMAssay Description:Antagonist activity against the Glucocorticoid Receptor (GR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118694(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity against the Glucocorticoid Receptor (GR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118694(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity against the Mineralocorticoid Receptor (MR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118688(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50:  61.1nMAssay Description:Agonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118693(6-(3-Chloro-5-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataEC50:  500nMAssay Description:Agonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50:  90nMAssay Description:Agonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed