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Found 14 Enz. Inhib. hit(s) with all data for entry = 50012522
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50113224((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-oxazol-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50116132((3-Methoxy-4-oxazol-5-yl-phenyl)-(4-methoxy-6-phen...)
Affinity DataIC50:  41nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120007((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-[1,3,4]...)
Affinity DataIC50:  44nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50112573(CHEMBL283256 | N-(3-Methoxy-4-oxazol-5-yl-phenyl)-...)
Affinity DataIC50:  52nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119999((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-[1,2,4]...)
Affinity DataIC50:  59nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120001((3-Methoxy-4-oxazol-5-yl-phenyl)-(4-methoxy-6-phen...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120006((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-4,5-dih...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120005((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-isoxazo...)
Affinity DataIC50:  120nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50116129(CHEMBL307547 | N*3*-(3-Methoxy-4-oxazol-5-yl-pheny...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120000((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-4H-[1,2...)
Affinity DataIC50:  190nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120004((3-Methoxy-4-oxazol-5-yl-phenyl)-(4-phenyl-thiazol...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120002((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-[1,3,4]...)
Affinity DataIC50:  330nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120003((3-Methoxy-4-oxazol-5-yl-phenyl)-(2-phenyl-thiazol...)
Affinity DataIC50:  760nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed