Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50012570
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120519((7-{[4-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-bu...)
Affinity DataIC50:  0.100nMAssay Description:Displacement of vitronectin from Human integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120520((7-{[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyryl...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120519((7-{[4-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-bu...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of vitronectin from Human integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120520((7-{[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyryl...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120517(CHEMBL109703 | {7-[(4-5,6,7,8-Tetrahydro-[1,8]naph...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120517(CHEMBL109703 | {7-[(4-5,6,7,8-Tetrahydro-[1,8]naph...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120523((7-{[4-(1H-Benzoimidazol-2-ylamino)-butyrylamino]-...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120523((7-{[4-(1H-Benzoimidazol-2-ylamino)-butyrylamino]-...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120516((7-{[4-(Pyridin-2-ylamino)-butyrylamino]-methyl}-6...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120518((7-{[5-(Pyridin-2-ylamino)-pentanoylamino]-methyl}...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120516((7-{[4-(Pyridin-2-ylamino)-butyrylamino]-methyl}-6...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120518((7-{[5-(Pyridin-2-ylamino)-pentanoylamino]-methyl}...)
Affinity DataIC50:  2.70nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120522((7-{[4-(Thiazol-2-ylamino)-butyrylamino]-methyl}-6...)
Affinity DataIC50:  20nMAssay Description:Displacement of vitronectin from Human integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120515((7-{[3-(Pyridin-2-ylamino)-propionylamino]-methyl}...)
Affinity DataIC50:  22nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120521((7-{[4-(Methyl-pyridin-2-yl-amino)-butyrylamino]-m...)
Affinity DataIC50:  40nMAssay Description:Displacement of vitronectin from Human integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120522((7-{[4-(Thiazol-2-ylamino)-butyrylamino]-methyl}-6...)
Affinity DataIC50:  45nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120521((7-{[4-(Methyl-pyridin-2-yl-amino)-butyrylamino]-m...)
Affinity DataIC50:  68nMAssay Description:Displacement of vitronectin from Human integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120520((7-{[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyryl...)
Affinity DataIC50:  110nMAssay Description:Displacement of vitronectin from Human integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120524(CHEMBL421890 | [7-({3-[(Pyridin-2-ylmethyl)-amino]...)
Affinity DataIC50:  119nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120519((7-{[4-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-bu...)
Affinity DataIC50:  330nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120524(CHEMBL421890 | [7-({3-[(Pyridin-2-ylmethyl)-amino]...)
Affinity DataIC50:  552nMAssay Description:Displacement of vitronectin from Human integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120515((7-{[3-(Pyridin-2-ylamino)-propionylamino]-methyl}...)
Affinity DataIC50:  584nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120521((7-{[4-(Methyl-pyridin-2-yl-amino)-butyrylamino]-m...)
Affinity DataIC50:  667nMAssay Description:Displacement of vitronectin from Human integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120524(CHEMBL421890 | [7-({3-[(Pyridin-2-ylmethyl)-amino]...)
Affinity DataIC50:  842nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120523((7-{[4-(1H-Benzoimidazol-2-ylamino)-butyrylamino]-...)
Affinity DataIC50:  1.02E+3nMAssay Description:Displacement of fibrinogen from Human integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120518((7-{[5-(Pyridin-2-ylamino)-pentanoylamino]-methyl}...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of vitronectin from Human integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120517(CHEMBL109703 | {7-[(4-5,6,7,8-Tetrahydro-[1,8]naph...)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of vitronectin from Human integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120515((7-{[3-(Pyridin-2-ylamino)-propionylamino]-methyl}...)
Affinity DataIC50:  1.70E+3nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120516((7-{[4-(Pyridin-2-ylamino)-butyrylamino]-methyl}-6...)
Affinity DataIC50:  4.36E+3nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50120522((7-{[4-(Thiazol-2-ylamino)-butyrylamino]-methyl}-6...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed