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Found 41 Enz. Inhib. hit(s) with all data for entry = 50012574
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120559(7-Methyl-2-[2-methyl-4-(3-piperidin-1-yl-propoxy)-...)
Affinity DataKi:  2nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120543(7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  2nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120537(8-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  3nMAssay Description:Antagonist activity for human histamine H3 receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120537(8-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120544(7-Methyl-2-[4-(3-pyrrolidin-1-yl-propoxy)-phenyl]-...)
Affinity DataKi:  5nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120542(2-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-imidazo[1,...)
Affinity DataKi:  6nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120562(2-[4-(3-Azepan-1-yl-propoxy)-phenyl]-7-methyl-imid...)
Affinity DataKi:  6nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120561(7-Methyl-2-[4-(4-piperidin-1-yl-but-1-ynyl)-phenyl...)
Affinity DataKi:  7nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120543(7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  10nMAssay Description:Compound was tested for its binding affinity for rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120551(2-[2-Fluoro-4-(3-piperidin-1-yl-propoxy)-phenyl]-7...)
Affinity DataKi:  10nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120549(CHEMBL70944 | Dimethyl-{3-[4-(8-methyl-imidazo[1,2...)
Affinity DataKi:  13nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120539(CHEMBL113236 | [4-(8-Methyl-imidazo[1,2-a]pyridin-...)
Affinity DataKi:  15nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120565(7-Methyl-2-[4-(4-piperidin-1-yl-butyl)-phenyl]-imi...)
Affinity DataKi:  17nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120556(7-Methyl-2-[4-((E)-4-piperidin-1-yl-but-1-enyl)-ph...)
Affinity DataKi:  22nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120547(2-[3-Methyl-4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  28nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120569(CHEMBL306911 | {3-[4-(8-Methyl-imidazo[1,2-a]pyrid...)
Affinity DataKi:  43nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120566(2-[3-Methoxy-4-(3-piperidin-1-yl-propoxy)-phenyl]-...)
Affinity DataKi:  69nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120570(8-Methyl-2-[4-(3-morpholin-4-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  80nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120567(CHEMBL114231 | N-[4-(8-Methyl-imidazo[1,2-a]pyridi...)
Affinity DataKi:  300nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120550(3-Piperidin-1-yl-propane-1-sulfonic acid [4-(8-met...)
Affinity DataKi:  500nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120538(CHEMBL445619 | Dibutyl-{3-[4-(3,8-dimethyl-imidazo...)
Affinity DataKi:  870nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120560(2-[4-(3-Imidazol-1-yl-propoxy)-phenyl]-8-methyl-im...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50022761(CHEMBL1204265 | CHEMBL71248 | Dibutyl-{3-[4-(7-met...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50022764(CHEMBL1204272 | CHEMBL71352 | Dibutyl-[3-(4-imidaz...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120568(2-[4-(3-Dibutylamino-propoxy)-phenyl]-imidazo[1,2-...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120540(CHEMBL71693 | Dibutyl-{3-[2-methoxy-4-(8-methyl-im...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120554(CHEMBL310907 | Dibutyl-{3-[4-(6-methyl-imidazo[1,2...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120555(CHEMBL113145 | Dibutyl-{3-[4-(5,7-dimethyl-imidazo...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120564(CHEMBL70313 | Dibutyl-{3-[4-(5-methyl-imidazo[1,2-...)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120546(CHEMBL302591 | {3-[4-(8-Benzyloxy-imidazo[1,2-a]py...)
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50022758(CHEMBL1204266 | CHEMBL308142 | Dibutyl-{3-[4-(8-me...)
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50022766(CHEMBL1204277 | CHEMBL70946 | {3-[4-(6-Bromo-imida...)
Affinity DataKi:  2.90E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120545(CHEMBL71530 | Dibutyl-{3-[2,6-dimethoxy-4-(8-methy...)
Affinity DataKi:  3.30E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120548(CHEMBL112163 | {3-[4-(8-Methyl-imidazo[1,2-a]pyrid...)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50022758(CHEMBL1204266 | CHEMBL308142 | Dibutyl-{3-[4-(8-me...)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120541(CHEMBL70874 | Dibutyl-{3-[3-methyl-4-(8-methyl-imi...)
Affinity DataKi:  4.20E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120558(CHEMBL114470 | Dibutyl-{3-[4-(6,8-dibromo-imidazo[...)
Affinity DataKi:  4.80E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120557(Benzyl-{3-[4-(8-methyl-imidazo[1,2-a]pyridin-2-yl)...)
Affinity DataKi:  5.40E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120552(CHEMBL70945 | {3-[4-(8-Methyl-imidazo[1,2-a]pyridi...)
Affinity DataKi:  7.90E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120563(CHEMBL71476 | Dibutyl-{3-[2-methyl-4-(8-methyl-imi...)
Affinity DataKi:  8.00E+3nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120553(CHEMBL71047 | Dibutyl-{3-[4-(8-nitro-imidazo[1,2-a...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity for human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed