Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50012605
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120982((S)-4-Acetylamino-4-[2-carboxy-1-((S)-1-{(S)-1-[(S...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120987(CHEMBL419930 | [(S)-1-((4S,6R,6aS)-6-Ethyl-4-metha...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120985(CHEMBL112200 | [(S)-1-((6R,6aS)-6-Ethyl-4-methanes...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120984(CHEMBL116118 | [(S)-1-((4S,6R,6aS)-4-Acetyl-6-ethy...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120987(CHEMBL419930 | [(S)-1-((4S,6R,6aS)-6-Ethyl-4-metha...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120986(CHEMBL326331 | [(S)-1-((4R,6R,6aS)-6-Ethyl-4-metha...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120985(CHEMBL112200 | [(S)-1-((6R,6aS)-6-Ethyl-4-methanes...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120982((S)-4-Acetylamino-4-[2-carboxy-1-((S)-1-{(S)-1-[(S...)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 2 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120982((S)-4-Acetylamino-4-[2-carboxy-1-((S)-1-{(S)-1-[(S...)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120986(CHEMBL326331 | [(S)-1-((4R,6R,6aS)-6-Ethyl-4-metha...)
Affinity DataIC50:  8.80E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120984(CHEMBL116118 | [(S)-1-((4S,6R,6aS)-4-Acetyl-6-ethy...)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120985(CHEMBL112200 | [(S)-1-((6R,6aS)-6-Ethyl-4-methanes...)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983(CHEMBL115136 | [(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethy...)
Affinity DataIC50:  1.47E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120984(CHEMBL116118 | [(S)-1-((4S,6R,6aS)-4-Acetyl-6-ethy...)
Affinity DataIC50:  1.72E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120985(CHEMBL112200 | [(S)-1-((6R,6aS)-6-Ethyl-4-methanes...)
Affinity DataIC50:  1.82E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120986(CHEMBL326331 | [(S)-1-((4R,6R,6aS)-6-Ethyl-4-metha...)
Affinity DataIC50:  1.93E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120986(CHEMBL326331 | [(S)-1-((4R,6R,6aS)-6-Ethyl-4-metha...)
Affinity DataIC50:  1.94E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983(CHEMBL115136 | [(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethy...)
Affinity DataIC50:  2.16E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120982((S)-4-Acetylamino-4-[2-carboxy-1-((S)-1-{(S)-1-[(S...)
Affinity DataIC50:  2.84E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120984(CHEMBL116118 | [(S)-1-((4S,6R,6aS)-4-Acetyl-6-ethy...)
Affinity DataIC50:  3.41E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120982((S)-4-Acetylamino-4-[2-carboxy-1-((S)-1-{(S)-1-[(S...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983(CHEMBL115136 | [(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethy...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983(CHEMBL115136 | [(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethy...)
Affinity DataIC50:  4.47E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed