Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 50012850
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123310(1,3-Diethyl-5-(1-methyl-1H-indol-3-ylmethylene)-2-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123291(3-Ethyl-5-[1-[5-(2-methyl-5-trifluoromethyl-2H-pyr...)
Affinity DataIC50:  140nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123293(2-Allyl-6,8-dimethoxy-9-methyl-1-thioxo-1,2-dihydr...)
Affinity DataIC50:  210nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123283(2-Allyl-6,8-dimethoxy-9-methyl-imidazo[1,5-a]indol...)
Affinity DataIC50:  210nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123285(2-Ethyl-8-methoxy-6-methoxymethoxy-3-thioxo-2,3-di...)
Affinity DataIC50:  280nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123288(2-Allyl-6,8-dimethoxy-3-thioxo-2,3-dihydro-imidazo...)
Affinity DataIC50:  280nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123289(3-{5-[3-Ethyl-4-oxo-2-thioxo-thiazolidin-(5Z)-ylid...)
Affinity DataIC50:  300nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123298(2-Ethyl-8-methoxy-6-(pyridin-2-ylmethoxy)-3-thioxo...)
Affinity DataIC50:  310nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123308(3-Ethyl-2-thioxo-5-[1-[5-(2-trifluoromethyl-phenyl...)
Affinity DataIC50:  320nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123287((2-Ethyl-8-methoxy-1-oxo-3-thioxo-2,3-dihydro-1H-i...)
Affinity DataIC50:  390nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123284(5-(5-Benzyloxy-1H-indol-3-ylmethylene)-1,3-diethyl...)
Affinity DataIC50:  400nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123307(1,3-Diethyl-5-(7-methyl-1H-indol-3-ylmethylene)-2-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123297(2-Allyl-6,8-dimethoxy-1-thioxo-1,2-dihydro-imidazo...)
Affinity DataIC50:  610nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123302(6,8-Dimethoxy-2-(3-morpholin-4-yl-propyl)-3-thioxo...)
Affinity DataIC50:  670nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123294(2-Allyl-6,7,8-trimethoxy-3-thioxo-2,3-dihydro-imid...)
Affinity DataIC50:  780nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123286(5-(1H-Indol-3-ylmethylene)-2-thioxo-1,3-di-o-tolyl...)
Affinity DataIC50:  790nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123305(1,3-Diethyl-5-(1H-indol-3-ylmethylene)-2-thioxo-di...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123313(2-Ethyl-6,8-dimethoxy-3-thioxo-2,3-dihydro-imidazo...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123296(2-Allyl-6,8-dimethoxy-9-methyl-3-thioxo-2,3-dihydr...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123281(2-Allyl-6-methoxy-3-thioxo-2,3-dihydro-imidazo[1,5...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123295(5-[1-(1H-Indol-3-yl)-meth-(E)-ylidene]-2-thioxo-1-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123309(6,8-Dimethoxy-2-phenethyl-3-thioxo-2,3-dihydro-imi...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123312(1,3-Diethyl-2-thioxo-5-[5-(2-trifluoromethyl-pheny...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123301(2-Allyl-8-methoxy-3-thioxo-2,3-dihydro-imidazo[1,5...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123304(3-[5-(1,3-Diethyl-4,6-dioxo-2-thioxo-tetrahydro-py...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123290(1,3-Diethyl-5-(5-methyl-thiophen-2-ylmethylene)-2-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123311(5-(5-Bromo-thiophen-2-ylmethylene)-1,3-diethyl-2-t...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123300(1,3-Diethyl-5-(5-nitro-1H-indol-3-ylmethylene)-2-t...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123282(1,3-Diethyl-5-(1H-indol-2-ylmethylene)-2-thioxo-di...)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123292(1,3-Diphenyl-2-thioxo-5-[5-(2-trifluoromethyl-phen...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123303(5-(1H-Indol-3-ylmethylene)-1,3-dimethyl-2-thioxo-d...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123306(1,3-Diethyl-5-(3-methyl-thiophen-2-ylmethylene)-2-...)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123299(3-[5-(4,6-Dioxo-1,3-diphenyl-2-thioxo-tetrahydro-p...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed