Compile Data Set for Download or QSAR
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Found 43 Enz. Inhib. hit(s) with all data for entry = 50013030
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataIC50:  0.300nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataIC50:  0.600nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125645(1-[4-((R)-6-Methoxy-indan-1-yl)-piperazin-1-yl]-2-...)
Affinity DataIC50:  1.5nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125647(1-[4-(6-Methoxy-indan-1-yl)-piperazin-1-yl]-2-meth...)
Affinity DataIC50:  1.5nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125634(CHEMBL19653 | Cyclopropyl-[4-((R)-6-methoxy-indan-...)
Affinity DataIC50:  1.60nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125644(4-((R)-6-Methoxy-indan-1-yl)-piperazine-1-carboxyl...)
Affinity DataIC50:  1.70nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125633(1-[4-(6-Methoxy-indan-1-yl)-piperazin-1-yl]-butan-...)
Affinity DataIC50:  2.30nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125639(CHEMBL19339 | Cyclopropyl-[4-(6-methoxy-indan-1-yl...)
Affinity DataIC50:  3nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125649(4-(6-Methoxy-indan-1-yl)-piperazine-1-carboxylic a...)
Affinity DataIC50:  3.10nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125636(1-[4-(6-Methoxy-indan-1-yl)-piperazin-1-yl]-propan...)
Affinity DataIC50:  32nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125638(1-[4-(6-Methoxy-indan-1-yl)-piperazin-1-yl]-ethano...)
Affinity DataIC50:  44nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125634(CHEMBL19653 | Cyclopropyl-[4-((R)-6-methoxy-indan-...)
Affinity DataIC50:  45nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125642(CHEMBL275205 | Cyclopropyl-[4-(7-methoxy-1,2,3,4-t...)
Affinity DataIC50:  75nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125637(CHEMBL19442 | Cyclopropyl-[4-(7-methoxy-naphthalen...)
Affinity DataIC50:  90nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125650(4-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-p...)
Affinity DataIC50:  94nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125635(1-[4-(6-Methoxy-indan-1-yl)-piperazin-1-yl]-pentan...)
Affinity DataIC50:  103nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125645(1-[4-((R)-6-Methoxy-indan-1-yl)-piperazin-1-yl]-2-...)
Affinity DataIC50:  116nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125639(CHEMBL19339 | Cyclopropyl-[4-(6-methoxy-indan-1-yl...)
Affinity DataIC50:  156nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125647(1-[4-(6-Methoxy-indan-1-yl)-piperazin-1-yl]-2-meth...)
Affinity DataIC50:  160nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125644(4-((R)-6-Methoxy-indan-1-yl)-piperazine-1-carboxyl...)
Affinity DataIC50:  200nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125641(1-[4-(2-Fluoro-5-methoxy-benzyl)-piperazin-1-yl]-2...)
Affinity DataIC50:  224nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125643(CHEMBL18747 | Cyclopropyl-[4-(2-fluoro-5-methoxy-b...)
Affinity DataIC50:  270nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125650(4-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-p...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125632(CHEMBL274731 | Cyclopropyl-[4-((S)-6-methoxy-indan...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125651(4-((S)-6-Methoxy-indan-1-yl)-piperazine-1-carboxyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125651(4-((S)-6-Methoxy-indan-1-yl)-piperazine-1-carboxyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125648(1-[4-(2-Fluoro-5-methoxy-benzyl)-piperazin-1-yl]-e...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125649(4-(6-Methoxy-indan-1-yl)-piperazine-1-carboxylic a...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125642(CHEMBL275205 | Cyclopropyl-[4-(7-methoxy-1,2,3,4-t...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125638(1-[4-(6-Methoxy-indan-1-yl)-piperazin-1-yl]-ethano...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125646(1-[4-((S)-6-Methoxy-indan-1-yl)-piperazin-1-yl]-2-...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125646(1-[4-((S)-6-Methoxy-indan-1-yl)-piperazin-1-yl]-2-...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125640(4-(7-Methoxy-naphthalen-1-yl)-piperazine-1-carboxy...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125636(1-[4-(6-Methoxy-indan-1-yl)-piperazin-1-yl]-propan...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125648(1-[4-(2-Fluoro-5-methoxy-benzyl)-piperazin-1-yl]-e...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125643(CHEMBL18747 | Cyclopropyl-[4-(2-fluoro-5-methoxy-b...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125641(1-[4-(2-Fluoro-5-methoxy-benzyl)-piperazin-1-yl]-2...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125640(4-(7-Methoxy-naphthalen-1-yl)-piperazine-1-carboxy...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT2 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125635(1-[4-(6-Methoxy-indan-1-yl)-piperazin-1-yl]-pentan...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125637(CHEMBL19442 | Cyclopropyl-[4-(7-methoxy-naphthalen...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125633(1-[4-(6-Methoxy-indan-1-yl)-piperazin-1-yl]-butan-...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125632(CHEMBL274731 | Cyclopropyl-[4-((S)-6-methoxy-indan...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125644(4-((R)-6-Methoxy-indan-1-yl)-piperazine-1-carboxyl...)
Affinity DataEC50:  2.40nMAssay Description:Effective concentration of the compound against human MT2 (Melatonin) receptor stably expressed in NIH3T3 cells in adenylyl cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed