Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50013094
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126493(2-(3-Amino-4-cyclobutylmethanesulfonyl-6-methyl-2-...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126483(2-[3-Amino-4-(cyclobutylmethyl-sulfamoyl)-6-methyl...)
Affinity DataKi:  0.75nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126495(2-(3-Amino-4-cyclopentylmethanesulfonyl-6-methyl-2...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126498(2-(3-Amino-6-methyl-2-oxo-4-phenylmethanesulfonyl-...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126499(2-[3-Amino-6-methyl-2-oxo-4-(thiophene-2-sulfonyl)...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126494(2-(3-Amino-4-cyclobutylsulfamoyl-6-methyl-2-oxo-2H...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126490(2-(3-Amino-4-cyclopropylmethanesulfonyl-6-methyl-2...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126486(CHEMBL32549 | N-(6-Amino-2-methyl-pyridin-3-ylmeth...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126491(2-(3-Amino-4-cyclohexanesulfonyl-6-methyl-2-oxo-2H...)
Affinity DataKi:  3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126488(2-(3-Amino-4-benzenesulfonyl-6-methyl-2-oxo-2H-pyr...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126485(CHEMBL416033 | N-(6-Amino-2-methyl-pyridin-3-ylmet...)
Affinity DataKi:  3.90nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126492(2-[3-Amino-4-(cyclopropylmethyl-sulfamoyl)-6-methy...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126496(2-(3-Amino-4-cyclopropylsulfamoyl-6-methyl-2-oxo-2...)
Affinity DataKi:  7.40nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126487(CHEMBL34614 | N-(6-Amino-2-methyl-pyridin-3-ylmeth...)
Affinity DataKi:  10nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126489(2-(3-Amino-4-cyclopropanesulfonyl-6-methyl-2-oxo-2...)
Affinity DataKi:  17nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126484(CHEMBL32686 | N-(6-Amino-2-methyl-pyridin-3-ylmeth...)
Affinity DataKi:  19nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126497(2-[3-Amino-6-methyl-2-oxo-4-(toluene-4-sulfonyl)-2...)
Affinity DataKi:  94nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126491(2-(3-Amino-4-cyclohexanesulfonyl-6-methyl-2-oxo-2H...)
Affinity DataKi:  260nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126499(2-[3-Amino-6-methyl-2-oxo-4-(thiophene-2-sulfonyl)...)
Affinity DataKi:  340nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126488(2-(3-Amino-4-benzenesulfonyl-6-methyl-2-oxo-2H-pyr...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126493(2-(3-Amino-4-cyclobutylmethanesulfonyl-6-methyl-2-...)
Affinity DataKi:  550nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126495(2-(3-Amino-4-cyclopentylmethanesulfonyl-6-methyl-2...)
Affinity DataKi:  630nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126483(2-[3-Amino-4-(cyclobutylmethyl-sulfamoyl)-6-methyl...)
Affinity DataKi:  740nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126497(2-[3-Amino-6-methyl-2-oxo-4-(toluene-4-sulfonyl)-2...)
Affinity DataKi:  800nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126492(2-[3-Amino-4-(cyclopropylmethyl-sulfamoyl)-6-methy...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126494(2-(3-Amino-4-cyclobutylsulfamoyl-6-methyl-2-oxo-2H...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126498(2-(3-Amino-6-methyl-2-oxo-4-phenylmethanesulfonyl-...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126485(CHEMBL416033 | N-(6-Amino-2-methyl-pyridin-3-ylmet...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126490(2-(3-Amino-4-cyclopropylmethanesulfonyl-6-methyl-2...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126489(2-(3-Amino-4-cyclopropanesulfonyl-6-methyl-2-oxo-2...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126496(2-(3-Amino-4-cyclopropylsulfamoyl-6-methyl-2-oxo-2...)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126486(CHEMBL32549 | N-(6-Amino-2-methyl-pyridin-3-ylmeth...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126487(CHEMBL34614 | N-(6-Amino-2-methyl-pyridin-3-ylmeth...)
Affinity DataKi:  6.30E+3nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126484(CHEMBL32686 | N-(6-Amino-2-methyl-pyridin-3-ylmeth...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed