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Found 10 Enz. Inhib. hit(s) with all data for entry = 50013274
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  5.60nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106443(1-(3,4-Dihydroxy-benzyl)-6,7-dihydroxy-isoquinolin...)
Affinity DataKi:  7.20nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128459(4-(3,4-Dihydroxy-benzyl)-6,7-dihydroxy-quinoline-2...)
Affinity DataKi:  8nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 3 (IGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128459(4-(3,4-Dihydroxy-benzyl)-6,7-dihydroxy-quinoline-2...)
Affinity DataKi:  13nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128462(7-Amino-4-(3,4-dihydroxy-benzyl)-6-hydroxy-quinoli...)
Affinity DataKi:  52nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128461(4-(3,4-Dihydroxy-benzyl)-7-fluoro-6-hydroxy-quinol...)
Affinity DataKi:  53nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128458(4-(3,4-Dihydroxy-benzyl)-6-hydroxy-quinoline-2,7-d...)
Affinity DataKi:  110nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128456(7-Chloro-4-(3,4-dihydroxy-benzyl)-6-hydroxy-quinol...)
Affinity DataKi:  240nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128457(7-Amino-4-(3,4-dihydroxy-benzyl)-6-methoxy-quinoli...)
Affinity DataKi:  5.30E+3nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128460(4-(3,4-Dihydroxy-benzyl)-quinoline-2,6-dicarboxyli...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed