Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50013330
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129227(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-isopro...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129246(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-tert-b...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129237(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 4-tert-b...)
Affinity DataIC50:  48nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129231(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 4-tert-b...)
Affinity DataIC50:  75nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129226(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid di-tert-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129224(5-Chloro-3-methyl-1H-pyrrole-2,4-dicarboxylic acid...)
Affinity DataIC50:  160nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129235(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-pentaf...)
Affinity DataIC50:  160nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129240(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-(1-eth...)
Affinity DataIC50:  260nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129241(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 4-tert-b...)
Affinity DataIC50:  340nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129239(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-(2-dim...)
Affinity DataIC50:  390nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129244(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-pyridi...)
Affinity DataIC50:  720nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129230(1,3,5-Trimethyl-1H-pyrrole-2,4-dicarboxylic acid 4...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory concentration required against rat mGluR1a in CHO cells using the CDP-DAG accumulation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129233(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 4-tert-b...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129222(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-pyrimi...)
Affinity DataIC50:  1.45E+3nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129225(5-Formyl-3-methyl-1H-pyrrole-2,4-dicarboxylic acid...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129242(3,5-Dimethyl-pyrrole-1,2,4-tricarboxylic acid 1,4-...)
Affinity DataIC50:  2.30E+3nMAssay Description:In vitro inhibitory concentration required against rat mGluR1a in CHO cells using the CDP-DAG accumulation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129229(5-(Cyclopropylmethyl-carbamoyl)-3-methyl-1H-pyrrol...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129223(5-Acetoxymethyl-3-methyl-1H-pyrrole-2,4-dicarboxyl...)
Affinity DataIC50:  2.70E+3nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129238(4-Methyl-5-(pyridin-2-ylsulfanylcarbonyl)-1H-pyrro...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129236(3-Methyl-5-(pyridin-2-ylsulfanylcarbonyl)-1H-pyrro...)
Affinity DataIC50:  3.20E+3nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129232(4-Methyl-1H-pyrrole-2,3,5-tricarboxylic acid 3-ter...)
Affinity DataIC50:  3.20E+3nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129228(1-(3-Methoxy-propyl)-3,5-dimethyl-1H-pyrrole-2,4-d...)
Affinity DataIC50:  5.80E+3nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129234(5-Hydroxymethyl-3-methyl-1H-pyrrole-2,4-dicarboxyl...)
Affinity DataIC50:  7.90E+3nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129243(1-Allyloxycarbonylmethyl-3,5-dimethyl-1H-pyrrole-2...)
Affinity DataIC50:  1.26E+4nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50129245(3,5-Dimethyl-1H-pyrrole-2,4-dicarboxylic acid 2-pr...)
Affinity DataIC50:  1.58E+4nMAssay Description:In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed