Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 50035306
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Dexamethasone binding to Glucocorticoid receptorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Dexamethasone stimulated transcriptional activity in CHO cells expressing glucocorticoid receptorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50129980(3,4,5-Trihydroxy-6-(3-{[4-((8S,11R,13S,14S,17S)-17...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Dexamethasone binding to Glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  410nMAssay Description:Inhibition of prednisilone-induced tyrosine aminotransferase (TAT) activity in rat hepatocytesMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50129980(3,4,5-Trihydroxy-6-(3-{[4-((8S,11R,13S,14S,17S)-17...)
Affinity DataIC50:  550nMAssay Description:Inhibition of Dexamethasone stimulated transcriptional activity in CHO cells expressing glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50129980(3,4,5-Trihydroxy-6-(3-{[4-((8S,11R,13S,14S,17S)-17...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of prednisilone-induced tyrosine aminotransferase (TAT) activity in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed