Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 50000095
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001265(3-(4-Amino-phenyl)-5,7-dichloro-4-hydroxy-1H-quino...)
Affinity DataKi:  18nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001266(5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID ...)
Affinity DataKi:  40nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001264(5,7-Dichloro-4-hydroxy-3-p-tolyl-1H-quinolin-2-one...)
Affinity DataKi:  300nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001268(5,7-Dichloro-4-hydroxy-3-(4-nitro-phenyl)-1H-quino...)
Affinity DataKi:  860nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001260(3-phenyl-4-hydroxyquinolin-2(1H)-one | 4-Hydroxy-3...)
Affinity DataKi:  4.50E+3nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM81975(4-hydroxyquinoline-2-carboxylic acid | CAS_492-27-...)
Affinity DataKi:  5.40E+3nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001265(3-(4-Amino-phenyl)-5,7-dichloro-4-hydroxy-1H-quino...)
Affinity DataIC50:  210nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001264(5,7-Dichloro-4-hydroxy-3-p-tolyl-1H-quinolin-2-one...)
Affinity DataIC50:  550nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001266(5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID ...)
Affinity DataIC50:  860nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001260(3-phenyl-4-hydroxyquinolin-2(1H)-one | 4-Hydroxy-3...)
Affinity DataIC50:  7.29E+3nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM81975(4-hydroxyquinoline-2-carboxylic acid | CAS_492-27-...)
Affinity DataIC50:  4.02E+4nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed