Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50036054
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001273(3-((2-Carbamoyl-ethylsulfanyl)-{3-[2-(7-chloro-qui...)
Affinity DataIC50:  0.300nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001285((E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(...)
Affinity DataIC50:  0.800nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001293(3-[{3-[2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(...)
Affinity DataIC50:  2.20nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230047(CHEMBL127877)
Affinity DataIC50:  3nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001296(3-{(2-Carboxy-ethylsulfanyl)-[3-(7-chloro-quinolin...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230045(CHEMBL340726)
Affinity DataIC50:  15nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001271(3-((2-Carboxy-ethylsulfanyl)-{3-[2-(7-chloro-quino...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230044(CHEMBL123577)
Affinity DataIC50:  39nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230074(CHEMBL126859)
Affinity DataIC50:  54nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001269(3-((2-Carboxy-ethylsulfanyl)-{3-[2-(7-chloro-quino...)
Affinity DataIC50:  57nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001288(3-[{3-[2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001289(3-{(2-Dimethylcarbamoyl-ethylsulfanyl)-[3-(quinoli...)
Affinity DataIC50:  89nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230078(CHEMBL128010)
Affinity DataIC50:  97nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001300(3-((2-Carboxy-ethylsulfanyl)-{3-[3-(7-chloro-quino...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230046(CHEMBL125799)
Affinity DataIC50:  270nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001295(CHEMBL338166 | dilithium; 3-((2-carboxy-ethylsulfa...)
Affinity DataIC50:  440nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230049(CHEMBL125027)
Affinity DataIC50:  480nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230043(CHEMBL125978)
Affinity DataIC50:  495nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50012434((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...)
Affinity DataIC50:  510nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230077(CHEMBL414242)
Affinity DataIC50:  560nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230042(CHEMBL127530)
Affinity DataIC50:  580nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001282(CHEMBL124741 | {3-[2-(6-Methyl-quinolin-2-yl)-viny...)
Affinity DataIC50:  930nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230075(CHEMBL126379)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230051(CHEMBL125139)
Affinity DataIC50:  1.43E+3nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230052(CHEMBL124760)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230050(CHEMBL124709)
Affinity DataIC50:  1.78E+3nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001280(2-(2-Pyridin-4-yl-vinyl)-quinoline | CHEMBL338876)
Affinity DataIC50:  3.30E+3nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001290(2-[(E)-2-phenylethenyl]quinoline | CHEMBL127579 | ...)
Affinity DataIC50:  6.00E+3nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001283(2-(2-Pyridin-3-yl-vinyl)-quinoline | CHEMBL127816)
Affinity DataIC50:  6.00E+3nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230076(CHEMBL339304)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50230048(CHEMBL127905)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001270(2-(2-(quinolin-2-yl)vinyl)phenol | 2-(2-Quinolin-2...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed