Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50013880
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135663(3-(4-Biphenyl-4-ylmethyl-piperazin-1-ylmethyl)-pyr...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135663(3-(4-Biphenyl-4-ylmethyl-piperazin-1-ylmethyl)-pyr...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135667(3-(4-Naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-p...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135670(3-(4-Naphthalen-1-ylmethyl-piperazin-1-ylmethyl)-p...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135663(3-(4-Biphenyl-4-ylmethyl-piperazin-1-ylmethyl)-pyr...)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro inhibitory concentration required against Tyrosine phosphatase SHP-2 in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135668(3-(4-Benzyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135668(3-(4-Benzyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135668(3-(4-Benzyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][...)
Affinity DataIC50:  9.00E+3nMAssay Description:In vitro inhibitory concentration required against Tyrosine phosphatase SHP-2 in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135668(3-(4-Benzyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][...)
Affinity DataIC50:  1.20E+4nMAssay Description:In vitro inhibitory concentration required against Leukocyte antigen related receptor phosphatase (LAR) in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50:  1.40E+4nMAssay Description:In vitro inhibitory concentration required against Tyrosine phosphatase SHP-2 in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135663(3-(4-Biphenyl-4-ylmethyl-piperazin-1-ylmethyl)-pyr...)
Affinity DataIC50:  1.50E+4nMAssay Description:In vitro inhibitory concentration required against Protein-tyrosine phosphatase alpha in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135663(3-(4-Biphenyl-4-ylmethyl-piperazin-1-ylmethyl)-pyr...)
Affinity DataIC50:  1.60E+4nMAssay Description:In vitro inhibitory concentration required against Leukocyte antigen related receptor phosphatase (LAR) in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135663(3-(4-Biphenyl-4-ylmethyl-piperazin-1-ylmethyl)-pyr...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135672(3-(4-Methyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135669(3-Piperidin-1-ylmethyl-pyrimido[5,4-e][1,2,4]triaz...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135664(3-Morpholin-4-ylmethyl-pyrimido[5,4-e][1,2,4]triaz...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135668(3-(4-Benzyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][...)
Affinity DataIC50:  2.40E+4nMAssay Description:In vitro inhibitory concentration required against Protein-tyrosine phosphatase alpha in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50:  2.80E+4nMAssay Description:In vitro inhibitory concentration required against Protein-tyrosine phosphatase alpha in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50:  2.80E+4nMAssay Description:In vitro inhibitory concentration required against Leukocyte antigen related receptor phosphatase (LAR) in the presence of 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135671(3-Piperazin-1-ylmethyl-pyrimido[5,4-e][1,2,4]triaz...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135667(3-(4-Naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-p...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135670(3-(4-Naphthalen-1-ylmethyl-piperazin-1-ylmethyl)-p...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135672(3-(4-Methyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][...)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135671(3-Piperazin-1-ylmethyl-pyrimido[5,4-e][1,2,4]triaz...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135666(2-[(5,7-Diamino-pyrimido[5,4-e][1,2,4]triazin-3-yl...)
Affinity DataIC50:  9.70E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135668(3-(4-Benzyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][...)
Affinity DataIC50:  9.80E+4nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135666(2-[(5,7-Diamino-pyrimido[5,4-e][1,2,4]triazin-3-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135665(3-(4-Phenyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 300 nM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135673(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135669(3-Piperidin-1-ylmethyl-pyrimido[5,4-e][1,2,4]triaz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135665(3-(4-Phenyl-piperazin-1-ylmethyl)-pyrimido[5,4-e][...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50135664(3-Morpholin-4-ylmethyl-pyrimido[5,4-e][1,2,4]triaz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed