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Found 38 Enz. Inhib. hit(s) with all data for entry = 50013985
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136685(CHEMBL337822 | [3-Furan-2-yl-3-(naphthalen-1-yloxy...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)
Affinity DataKi:  0.800nMAssay Description:Ability to inhibit the reuptake of 5-HT at human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136672(CHEMBL342716 | [3-(4-Fluoro-phenyl)-3-(naphthalen-...)
Affinity DataKi:  0.950nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136683(CHEMBL142028 | Methyl-[3-(naphthalen-1-yloxy)-3-th...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136680(CHEMBL424660 | N-methyl-3-(1-naphthyloxy)-3-(2-thi...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136679(CHEMBL141741 | Methyl-[3-(naphthalen-1-yloxy)-3-o-...)
Affinity DataKi:  2nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136689(CHEMBL141114 | Methyl-[3-(naphthalen-1-yloxy)-3-p-...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136690(CHEMBL337791 | [3-(3-Methoxy-phenyl)-3-(naphthalen...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136691(CHEMBL139106 | [3-(2-Methoxy-phenyl)-3-(naphthalen...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136682(CHEMBL141681 | Methyl-[3-(naphthalen-1-yloxy)-3-ph...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136686(CHEMBL415244 | [3-(4-Methoxy-phenyl)-3-(naphthalen...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136688(CHEMBL139245 | [3-(4-Chloro-phenyl)-3-(naphthalen-...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136675(CHEMBL139277 | Methyl-[3-(naphthalen-1-yloxy)-3-m-...)
Affinity DataKi:  4nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136676(CHEMBL139168 | [3-(4-Bromo-phenyl)-3-(naphthalen-1...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136670(CHEMBL138031 | Methyl-[3-(naphthalen-1-yloxy)-3-th...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)
Affinity DataKi:  7.5nMAssay Description:Ability to inhibit the reuptake of NE at human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136678(CHEMBL337798 | [3-(3-Bromo-phenyl)-3-(naphthalen-1...)
Affinity DataKi:  7.60nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136677(CHEMBL334929 | Methyl-[3-(naphthalen-1-yloxy)-3-(2...)
Affinity DataKi:  10nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136673(CHEMBL137936 | Methyl-[3-(naphthalen-1-yloxy)-3-(4...)
Affinity DataKi:  15nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136687(CHEMBL141974 | Methyl-[3-(naphthalen-1-yloxy)-3-(3...)
Affinity DataKi:  19nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136685(CHEMBL337822 | [3-Furan-2-yl-3-(naphthalen-1-yloxy...)
Affinity DataKi:  20nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136682(CHEMBL141681 | Methyl-[3-(naphthalen-1-yloxy)-3-ph...)
Affinity DataKi:  20nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136680(CHEMBL424660 | N-methyl-3-(1-naphthyloxy)-3-(2-thi...)
Affinity DataKi:  20nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136683(CHEMBL142028 | Methyl-[3-(naphthalen-1-yloxy)-3-th...)
Affinity DataKi:  21nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136684(CHEMBL138195 | Methyl-[4-(naphthalen-1-yloxy)-buty...)
Affinity DataKi:  31nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136689(CHEMBL141114 | Methyl-[3-(naphthalen-1-yloxy)-3-p-...)
Affinity DataKi:  36nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136675(CHEMBL139277 | Methyl-[3-(naphthalen-1-yloxy)-3-m-...)
Affinity DataKi:  40nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136672(CHEMBL342716 | [3-(4-Fluoro-phenyl)-3-(naphthalen-...)
Affinity DataKi:  42nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136670(CHEMBL138031 | Methyl-[3-(naphthalen-1-yloxy)-3-th...)
Affinity DataKi:  55nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136678(CHEMBL337798 | [3-(3-Bromo-phenyl)-3-(naphthalen-1...)
Affinity DataKi:  67nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136687(CHEMBL141974 | Methyl-[3-(naphthalen-1-yloxy)-3-(3...)
Affinity DataKi:  70nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136686(CHEMBL415244 | [3-(4-Methoxy-phenyl)-3-(naphthalen...)
Affinity DataKi:  74nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136681(CHEMBL343324 | Methyl-[3-(naphthalen-1-yloxy)-prop...)
Affinity DataKi:  75nMAssay Description:Binding affinity to serotonin transporter, using [3H]-citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136688(CHEMBL139245 | [3-(4-Chloro-phenyl)-3-(naphthalen-...)
Affinity DataKi:  78nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136690(CHEMBL337791 | [3-(3-Methoxy-phenyl)-3-(naphthalen...)
Affinity DataKi:  81nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136679(CHEMBL141741 | Methyl-[3-(naphthalen-1-yloxy)-3-o-...)
Affinity DataKi:  110nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50136676(CHEMBL139168 | [3-(4-Bromo-phenyl)-3-(naphthalen-1...)
Affinity DataKi:  160nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)
Affinity DataKi:  240nMAssay Description:Ability to inhibit the reuptake of dopamine at human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank