Compile Data Set for Download or QSAR
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Found 47 Enz. Inhib. hit(s) with all data for entry = 50014133
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138607(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  77nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138628(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  105nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138619(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138602(CHEMBL152968 | N-Biphenyl-3-yl-2-{4-[(R)-2-hydroxy...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138617(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138625(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  330nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138627(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  360nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138598(CHEMBL153741 | N-Biphenyl-4-yl-2-{4-[(R)-2-hydroxy...)
Affinity DataIC50:  460nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138629(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  610nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138609(CHEMBL155284 | N-[1-((S)-4-Fluoro-phenyl)-ethyl]-2...)
Affinity DataIC50:  710nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138611(CHEMBL150614 | N-(9-Ethyl-9H-carbazol-3-yl)-2-{4-[...)
Affinity DataIC50:  850nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138606(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  860nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138613(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138626(CHEMBL152947 | N-(4-Chloro-benzyl)-2-{4-[(R)-2-hyd...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138618(CHEMBL152844 | N-[4-(4-Chloro-phenoxy)-phenyl]-2-{...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138630(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138599(CHEMBL154751 | N-(2,6-Dimethyl-phenyl)-2-{4-[(R)-2...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138604(CHEMBL153159 | N-Benzyl-2-{4-[(R)-2-hydroxy-3-(2-m...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138623(CHEMBL357278 | N-(4-Chloro-3-trifluoromethyl-pheny...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138621(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138610(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138615(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138601(CHEMBL153122 | N-Cyclohexylmethyl-2-{4-[(R)-2-hydr...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138600(CHEMBL152941 | N-Benzo[1,2,5]thiadiazol-4-yl-2-{4-...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138602(CHEMBL152968 | N-Biphenyl-3-yl-2-{4-[(R)-2-hydroxy...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of cytochrome P450 1A2 of isolated guinea pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138631(CHEMBL153650 | N-(3,4-Dichloro-phenyl)-2-{4-[(R)-2...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138622(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138598(CHEMBL153741 | N-Biphenyl-4-yl-2-{4-[(R)-2-hydroxy...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of cytochrome P450 3A4 of isolated guinea pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138614(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138612(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138620(CHEMBL155166 | N-Cyclohexyl-2-{4-[(R)-2-hydroxy-3-...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138624(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138616(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138608(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138599(CHEMBL154751 | N-(2,6-Dimethyl-phenyl)-2-{4-[(R)-2...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of cytochrome P450 3A4 of isolated guinea pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138602(CHEMBL152968 | N-Biphenyl-3-yl-2-{4-[(R)-2-hydroxy...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of cytochrome P450 2C9 of isolated guinea pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138605(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138597(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138598(CHEMBL153741 | N-Biphenyl-4-yl-2-{4-[(R)-2-hydroxy...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of cytochrome P450 2C9 of isolated guinea pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138598(CHEMBL153741 | N-Biphenyl-4-yl-2-{4-[(R)-2-hydroxy...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of cytochrome P450 1A2 of isolated guinea pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal acyl-coenzyme A oxidase 1(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138603(2-{4-[(R)-2-Hydroxy-3-(2-methyl-benzothiazol-5-ylo...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138602(CHEMBL152968 | N-Biphenyl-3-yl-2-{4-[(R)-2-hydroxy...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of cytochrome P450 3A4 of isolated guinea pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138611(CHEMBL150614 | N-(9-Ethyl-9H-carbazol-3-yl)-2-{4-[...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of cytochrome P450 3A4 of isolated guinea pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138611(CHEMBL150614 | N-(9-Ethyl-9H-carbazol-3-yl)-2-{4-[...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of cytochrome P450 1A2 of isolated guinea pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138599(CHEMBL154751 | N-(2,6-Dimethyl-phenyl)-2-{4-[(R)-2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of cytochrome P450 1A2 of isolated guinea pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138599(CHEMBL154751 | N-(2,6-Dimethyl-phenyl)-2-{4-[(R)-2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of cytochrome P450 2C9 of isolated guinea pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138611(CHEMBL150614 | N-(9-Ethyl-9H-carbazol-3-yl)-2-{4-[...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of cytochrome P450 2C9 of isolated guinea pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed