Compile Data Set for Download or QSAR
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Found 12 Enz. Inhib. hit(s) with all data for entry = 50014170
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50138996(1-{4-[3-Fluoro-5-(4-methoxy-tetrahydro-pyran-4-yl)...)
Affinity DataIC50:  60nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) of human whole blood (HWB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50138992(1-{4-[3-Fluoro-5-(4-methylsulfanyl-tetrahydro-pyra...)
Affinity DataIC50:  72nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) of human whole blood (HWB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50138997(1-{4-[3-(4-Ethoxy-tetrahydro-pyran-4-yl)-5-fluoro-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) of human whole blood (HWB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139002(1-(4-{3-Fluoro-5-[4-(2-methyl-imidazol-1-yl)-benzy...)
Affinity DataIC50:  130nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) of human whole blood (HWB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50138994(4-{3-Fluoro-5-[4-(2-methyl-imidazol-1-yl)-benzylox...)
Affinity DataIC50:  200nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) of human whole blood (HWB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139000(4-{3-Fluoro-5-[4-(2-methyl-imidazol-1-yl)-benzylox...)
Affinity DataIC50:  280nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) of human whole blood (HWB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50138993(4-{3-Fluoro-5-[4-(2-methyl-imidazol-1-yl)-benzylox...)
Affinity DataIC50:  340nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) of human whole blood (HWB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50138998(4-{3-Fluoro-5-[4-(2-methyl-imidazol-1-yl)-benzylox...)
Affinity DataIC50:  810nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) of human whole blood (HWB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50138999(4-{3-Fluoro-5-[4-(2-methyl-imidazol-1-yl)-benzylox...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) of human whole blood (HWB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139001(1-{4-[3-Fluoro-5-(4-methanesulfinyl-tetrahydro-pyr...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) of human whole blood (HWB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50138995(4-{3-Fluoro-5-[4-(2-methyl-imidazol-1-yl)-benzylox...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) of human whole blood (HWB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50138991(1-{4-[3-Fluoro-5-(4-methanesulfonyl-tetrahydro-pyr...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of 5-Lipoxygenase (5-LO) of human whole blood (HWB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed