Compile Data Set for Download or QSAR
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Found 159 Enz. Inhib. hit(s) with all data for entry = 50014775
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147315(2-(4-(3-fluorophenyl)piperidine-1-carbonyl)-4-(2-m...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147299(4-Butyl-3-methyl-2-(4-methyl-piperidine-1-carbonyl...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147297(4-Isopropyl-2-[4-(3-methoxy-phenyl)-piperazine-1-c...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147251(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147270(3-Methyl-4-(2-phenoxy-ethyl)-2-(piperidine-1-carbo...)
Affinity DataIC50:  2nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147243(4-Isopropyl-3-methyl-2-(piperidine-1-carbonyl)-2H-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147257(4-(2-Ethoxy-ethyl)-3-methyl-2-(4-methyl-piperidine...)
Affinity DataIC50:  3nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147281(4-Isobutyl-3-methyl-2-(4-methyl-piperidine-1-carbo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147251(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147279(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147267(4-Cyclohexyl-3-methyl-2-(4-methyl-piperidine-1-car...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147272(4-(2-Methoxy-ethyl)-3-methyl-2-(4-m-tolyl-piperidi...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147245(4-Isobutyl-3-methyl-2-(4-phenyl-piperidine-1-carbo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147270(3-Methyl-4-(2-phenoxy-ethyl)-2-(piperidine-1-carbo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147241(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147253(2-(4-(3-fluorophenyl)piperidine-1-carbonyl)-4-isop...)
Affinity DataIC50:  4nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147289(4-Isobutyl-3-methyl-2-(piperidine-1-carbonyl)-2H-i...)
Affinity DataIC50:  5nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147260(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147248(4-(2-Methoxy-ethyl)-3-methyl-2-(4-phenyl-piperidin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147303(4-Benzyl-3-methyl-2-(piperidine-1-carbonyl)-2H-iso...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147298(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147244(1-(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carbo...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147300(4-(4-Chloro-phenylsulfanyl)-3-methyl-2-(piperidine...)
Affinity DataIC50:  6nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147280(3-Methyl-2-(4-methyl-piperidine-1-carbonyl)-4-(tet...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147234(4-Isopropyl-3-methyl-2-(4-phenyl-piperazine-1-carb...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147282(3-Methyl-4-phenylsulfanyl-2-(piperidine-1-carbonyl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147283(4-Isopropyl-3-methyl-2-(4-methyl-piperidine-1-carb...)
Affinity DataIC50:  6nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147276(4-Cyclopentyl-3-methyl-2-(piperidine-1-carbonyl)-2...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147271(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147296(4-Butyl-3-methyl-2-(piperidine-1-carbonyl)-2H-isox...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147269(2-(3,3-Dimethyl-piperidine-1-carbonyl)-4-isopropyl...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147262(4-Isopropyl-3-methyl-2-(thiomorpholine-4-carbonyl)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147259(4-Cyclopentyl-3-methyl-2-(4-phenyl-piperidine-1-ca...)
Affinity DataIC50:  8nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147263(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147241(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147285(4-(2-Methoxy-ethyl)-3-methyl-2-(piperidine-1-carbo...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147299(4-Butyl-3-methyl-2-(4-methyl-piperidine-1-carbonyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147279(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147245(4-Isobutyl-3-methyl-2-(4-phenyl-piperidine-1-carbo...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147247(3-Methyl-2-(piperidine-1-carbonyl)-4-(tetrahydro-t...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147264(4-Cyclohexyl-3-methyl-2-(piperidine-1-carbonyl)-2H...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147248(4-(2-Methoxy-ethyl)-3-methyl-2-(4-phenyl-piperidin...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147253(2-(4-(3-fluorophenyl)piperidine-1-carbonyl)-4-isop...)
Affinity DataIC50:  12nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147298(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  12nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147307(4-Isopropyl-3-methyl-2-(4-phenyl-piperidine-1-carb...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147238(3,4-Dimethyl-2-(piperidine-1-carbonyl)-2H-isoxazol...)
Affinity DataIC50:  13nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147297(4-Isopropyl-2-[4-(3-methoxy-phenyl)-piperazine-1-c...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147273(4-tert-Butyl-3-methyl-2-(piperidine-1-carbonyl)-2H...)
Affinity DataIC50:  14nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147255(3-Methyl-4-phenyl-2-(piperidine-1-carbonyl)-2H-iso...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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