Compile Data Set for Download or QSAR
maximum 50k data
Found 39 Enz. Inhib. hit(s) with all data for entry = 50037324
TargetSodium/bile acid cotransporter(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150325(3-[4-(4-{[Benzyl-(3-methanesulfonylamino-2-methyl-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of [3H]taurocholate uptake in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(CHEMBL182610 | N-{3-[Benzyl-(4-phenoxy-benzyl)-ami...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/bile acid cotransporter(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150349(CHEMBL266407 | Methanesulfonamide derivative)
Affinity DataIC50:  4nMAssay Description:Inhibition of [3H]taurocholate uptake in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150347(3-[4-(4-{[(2,4-Difluoro-benzyl)-(3-methanesulfonyl...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150326(4-[4-(4-{[Benzyl-(3-methanesulfonylamino-2-methyl-...)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144471(CHEMBL68083 | N-{3-[Benzyl-(2,4-difluoro-benzyl)-a...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150349(CHEMBL266407 | Methanesulfonamide derivative)
Affinity DataIC50:  17nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144457(CHEMBL419633 | N-(3-Dibenzylamino-2-methyl-phenyl)...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150325(3-[4-(4-{[Benzyl-(3-methanesulfonylamino-2-methyl-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150343(CHEMBL268220 | Methanesulfonamide derivative)
Affinity DataIC50:  50nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150342(4-(3-{[(3-Methanesulfonylamino-2-methyl-phenyl)-(4...)
Affinity DataIC50:  56nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150353(CHEMBL264841 | Methanesulfonamide derivative)
Affinity DataIC50:  57nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150344(CHEMBL405444 | Methanesulfonamide derivative)
Affinity DataIC50:  62nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150350(CHEMBL182726 | [3-(4-{[Benzyl-(3-methanesulfonylam...)
Affinity DataIC50:  63nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150346(CHEMBL263506 | Methanesulfonamide derivative)
Affinity DataIC50:  93nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150338(CHEMBL181604 | N-{3-[(2,4-Difluoro-benzyl)-(4-phen...)
Affinity DataIC50:  95nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144471(CHEMBL68083 | N-{3-[Benzyl-(2,4-difluoro-benzyl)-a...)
Affinity DataIC50:  100nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150341(4-(4-{[(3-Methanesulfonylamino-2-methyl-phenyl)-(4...)
Affinity DataIC50:  170nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150347(3-[4-(4-{[(2,4-Difluoro-benzyl)-(3-methanesulfonyl...)
Affinity DataIC50:  220nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150321(CHEMBL182610 | N-{3-[Benzyl-(4-phenoxy-benzyl)-ami...)
Affinity DataIC50:  235nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144457(CHEMBL419633 | N-(3-Dibenzylamino-2-methyl-phenyl)...)
Affinity DataIC50:  250nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150352(CHEMBL387269 | Methanesulfonamide derivative)
Affinity DataIC50:  260nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  270nMAssay Description:Inhibition of dexamethasone-induced GR-mediated tyrosine amino transferase activity in rat hepatocytesMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150323(4-[3-(4-{[Benzyl-(3-methanesulfonylamino-2-methyl-...)
Affinity DataIC50:  270nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150354(CHEMBL385369 | Methanesulfonamide derivative)
Affinity DataIC50:  270nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150342(4-(3-{[(3-Methanesulfonylamino-2-methyl-phenyl)-(4...)
Affinity DataIC50:  310nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150348((R)-4-((3S,5R,7R,8R,9S,10S,12S,13R,14S,17R)-3-{2-[...)
Affinity DataIC50:  310nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150344(CHEMBL405444 | Methanesulfonamide derivative)
Affinity DataIC50:  390nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150349(CHEMBL266407 | Methanesulfonamide derivative)
Affinity DataIC50:  450nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150325(3-[4-(4-{[Benzyl-(3-methanesulfonylamino-2-methyl-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150348((R)-4-((3S,5R,7R,8R,9S,10S,12S,13R,14S,17R)-3-{2-[...)
Affinity DataIC50:  560nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150353(CHEMBL264841 | Methanesulfonamide derivative)
Affinity DataIC50:  590nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150326(4-[4-(4-{[Benzyl-(3-methanesulfonylamino-2-methyl-...)
Affinity DataIC50:  670nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150351(3-(4-{[Benzyl-(3-methanesulfonylamino-2-methyl-phe...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150351(3-(4-{[Benzyl-(3-methanesulfonylamino-2-methyl-phe...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150338(CHEMBL181604 | N-{3-[(2,4-Difluoro-benzyl)-(4-phen...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150350(CHEMBL182726 | [3-(4-{[Benzyl-(3-methanesulfonylam...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/bile acid cotransporter(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50375594(TAUROCHOLATE)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of [3H]taurocholate uptake in rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed