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Found 17 Enz. Inhib. hit(s) with all data for entry = 50015043
LigandPNGBDBM50410179(CHEMBL2096800)
Affinity DataIC50:  0.140nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50410179(CHEMBL2096800)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against Gamma-secretase from APP-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50410182(CHEMBL2096799)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50410183(CHEMBL2096801)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150691(311951 | CHEMBL437635)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150696(CHEMBL436787 | methyl 2-[(2R,3R)-2-[(2R)-2-{2-[(2R...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150689(311952 | CHEMBL411599)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50410178(CHEMBL2096802)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150693(CHEMBL415576 | methyl 2-[(2R)-2-[(2R,3S)-3-(benzyl...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150690(CHEMBL409305 | methyl 2-[(2S,3S)-2-[(2S)-2-{2-[(2S...)
Affinity DataIC50:  360nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150688(311440 | CHEMBL413823)
Affinity DataIC50:  780nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150694(311383 | CHEMBL437440)
Affinity DataIC50:  910nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150687(CHEMBL410969 | methyl 2-[(2S,3S)-2-[(2S)-2-{2-[(2S...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50410181(CHEMBL2096796)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150695(CHEMBL414031 | methyl 2-[(2S,3S)-2-[(2S)-2-{2-[(2S...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50410180(CHEMBL2096797)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150692(CHEMBL263474 | methyl 2-[(2S)-2-[(2S,3R)-3-(benzyl...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed