Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50015073
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)
Affinity DataKi:  1nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)
Affinity DataKi:  2nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50145710(2-Methyl-3-{4-[2-(5-methyl-2-thiophen-2-yl-oxazol-...)
Affinity DataKi:  3nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50145710(2-Methyl-3-{4-[2-(5-methyl-2-thiophen-2-yl-oxazol-...)
Affinity DataKi:  4nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124389(2,2-Dimethyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]is...)
Affinity DataKi:  10nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124389(2,2-Dimethyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]is...)
Affinity DataKi:  20nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50131503(5-{3-[3-(4-Phenoxy-2-propyl-phenoxy)-propoxy]-phen...)
Affinity DataKi:  30nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataKi:  50nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50131503(5-{3-[3-(4-Phenoxy-2-propyl-phenoxy)-propoxy]-phen...)
Affinity DataKi:  60nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50109551((2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY...)
Affinity DataKi:  90nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50100442(2-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataKi:  170nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Mus musculus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28798((2S)-2-ethoxy-3-(4-{2-[4-(methanesulfonyloxy)pheny...)
Affinity DataKi:  200nMAssay Description:Binding affinity for murine peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50075315(5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...)
Affinity DataKi:  230nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50075315(5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...)
Affinity DataKi:  330nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50100442(2-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataKi:  550nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50109551((2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY...)
Affinity DataKi:  980nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28798((2S)-2-ethoxy-3-(4-{2-[4-(methanesulfonyloxy)pheny...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151000(5-{4-[2-(4-Ethyl-phenyl)-ethoxy]-benzyl}-thiazolid...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151000(5-{4-[2-(4-Ethyl-phenyl)-ethoxy]-benzyl}-thiazolid...)
Affinity DataEC50:  580nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50131503(5-{3-[3-(4-Phenoxy-2-propyl-phenoxy)-propoxy]-phen...)
Affinity DataEC50:  10nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50109547((S)-3-(4-(2-CARBAZOL-9-YL-ETHOXY)-PHENYL)-2-ETHOXY...)
Affinity DataEC50:  360nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50109551((2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY...)
Affinity DataEC50:  570nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28701(2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-...)
Affinity DataEC50:  5.00E+4nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50100442(2-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataEC50:  880nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataEC50:  40nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50085047(2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl e...)
Affinity DataEC50:  5.50E+4nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50100442(2-{4-[2-(2-Biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)
Affinity DataEC50:  150nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124389(2,2-Dimethyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]is...)
Affinity DataEC50:  4nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50145710(2-Methyl-3-{4-[2-(5-methyl-2-thiophen-2-yl-oxazol-...)
Affinity DataEC50:  4nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)
Affinity DataEC50:  2nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50109547((S)-3-(4-(2-CARBAZOL-9-YL-ETHOXY)-PHENYL)-2-ETHOXY...)
Affinity DataEC50:  170nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50109551((2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY...)
Affinity DataEC50:  3.20E+3nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28798((2S)-2-ethoxy-3-(4-{2-[4-(methanesulfonyloxy)pheny...)
Affinity DataEC50:  1.70E+3nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)
Affinity DataEC50:  0.200nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50150999(2-Isopropoxy-3-{4-[5-(4-isopropyl-phenyl)-[1,2,4]o...)
Affinity DataEC50:  10nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Mus musculus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28798((2S)-2-ethoxy-3-(4-{2-[4-(methanesulfonyloxy)pheny...)
Affinity DataEC50:  250nMAssay Description:Effective concentration against murine peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50131503(5-{3-[3-(4-Phenoxy-2-propyl-phenoxy)-propoxy]-phen...)
Affinity DataEC50:  30nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50145710(2-Methyl-3-{4-[2-(5-methyl-2-thiophen-2-yl-oxazol-...)
Affinity DataEC50:  9nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50150999(2-Isopropoxy-3-{4-[5-(4-isopropyl-phenyl)-[1,2,4]o...)
Affinity DataEC50:  4nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124389(2,2-Dimethyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]is...)
Affinity DataEC50:  20nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50085042(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
Affinity DataEC50:  3.00E+4nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50150998(((4-Methoxy-phenoxycarbonyl)-{4-[2-(5-methyl-2-phe...)
Affinity DataEC50:  120nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50075315(5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50075315(5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...)
Affinity DataEC50:  800nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28701(2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-...)
Affinity DataEC50:  6.00E+4nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50085042(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
Affinity DataEC50:  3.00E+5nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50150998(((4-Methoxy-phenoxycarbonyl)-{4-[2-(5-methyl-2-phe...)
Affinity DataEC50:  240nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed