Compile Data Set for Download or QSAR
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Found 18 Enz. Inhib. hit(s) with all data for entry = 50015391
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155562(1-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50:  52nMAssay Description:Inhibitory concentration required to inhibit Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155567(1-(3-Dimethylamino-phenyl)-3-[4-methyl-3-(4-pyridi...)
Affinity DataIC50:  56nMAssay Description:Inhibitory concentration required to inhibit Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155560(1-(3-Chloro-phenyl)-3-[4-methyl-3-(4-pyridin-3-yl-...)
Affinity DataIC50:  175nMAssay Description:Inhibitory concentration required to inhibit Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155568(1-(3-Diethylamino-phenyl)-3-[4-methyl-3-(4-pyridin...)
Affinity DataIC50:  280nMAssay Description:Inhibitory concentration required to inhibit Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155567(1-(3-Dimethylamino-phenyl)-3-[4-methyl-3-(4-pyridi...)
Affinity DataIC50:  573nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155562(1-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50:  720nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155563(1-{2-[(Cyclohexyl-methyl-amino)-methyl]-phenyl}-3-...)
Affinity DataIC50:  870nMAssay Description:Inhibitory concentration required to inhibit Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155565(CHEMBL185775 | Piperidine-1-carboxylic acid [4-met...)
Affinity DataIC50:  930nMAssay Description:Inhibitory concentration required to inhibit Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155568(1-(3-Diethylamino-phenyl)-3-[4-methyl-3-(4-pyridin...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155574(1-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration required to inhibit Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155560(1-(3-Chloro-phenyl)-3-[4-methyl-3-(4-pyridin-3-yl-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155557(1-(4-Diethylamino-phenyl)-3-[4-methyl-3-(4-pyridin...)
Affinity DataIC50: >3.40E+3nMAssay Description:Inhibitory concentration required to inhibit Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155561(4-Methyl-piperazine-1-carboxylic acid [4-methyl-3-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155559(1-(4-Dimethylamino-phenyl)-3-[4-methyl-3-(4-pyridi...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibitory concentration required to inhibit Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155575(1-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155565(CHEMBL185775 | Piperidine-1-carboxylic acid [4-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155557(1-(4-Diethylamino-phenyl)-3-[4-methyl-3-(4-pyridin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155559(1-(4-Dimethylamino-phenyl)-3-[4-methyl-3-(4-pyridi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed