Found 35 Enz. Inhib. hit(s) with all data for entry = 50000435 TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine rec...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 7.40nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 7.70nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine rec...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 9.30nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine rec...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 9.90nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Muscarinic acetylcholine receptor M...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 111nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 173nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 178nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 209nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 246nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 248nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 258nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Institute Of Research
Curated by ChEMBL
Institute Of Research
Curated by ChEMBL
Affinity DataKi: 298nMAssay Description:Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
