Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 50015657
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159110(1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...)
Affinity DataKi:  0.200nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50146832(1-(3,4-Dimethoxy-phenyl)-4-[4-(1-ethyl-propyl)-pip...)
Affinity DataKi:  0.380nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM22541(Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...)
Affinity DataKi:  0.600nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159113(2-(4-Cyclopropyl-piperazin-1-yl)-6-pyrazol-1-yl-qu...)
Affinity DataKi:  1.10nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159114(CHEMBL179234 | Cyclopropyl-[2-(4-cyclopropyl-piper...)
Affinity DataKi:  1.80nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50120543(7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  2nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159116(2-[4-(1-Ethyl-propyl)-piperazin-1-yl]-quinoline | ...)
Affinity DataKi:  2.90nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159122(2-(4-Cyclopropyl-piperazin-1-yl)-6-methoxy-quinoli...)
Affinity DataKi:  3nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159121(2-(4-Cyclopropyl-piperazin-1-yl)-quinoline-6-carbo...)
Affinity DataKi:  4.80nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159120(2-(4-Propyl-piperazin-1-yl)-quinoline | CHEMBL1804...)
Affinity DataKi:  6nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159108(2-(4-Isopropyl-piperazin-1-yl)-quinoline | CHEMBL3...)
Affinity DataKi:  6.80nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159109(2-(4-Cyclopropyl-piperazin-1-yl)-quinoline | CHEMB...)
Affinity DataKi:  13nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKi:  14nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159111((R)-2-Quinolin-2-yl-octahydro-pyrido[1,2-a]pyrazin...)
Affinity DataKi:  18nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159118(6-Chloro-2-(4-cyclopropyl-piperazin-1-yl)-quinolin...)
Affinity DataKi:  24nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159117(2-(4-Cyclopentyl-piperazin-1-yl)-quinoline | CHEMB...)
Affinity DataKi:  28nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159123(6-Cyclohexyl-2-(4-cyclopropyl-piperazin-1-yl)-quin...)
Affinity DataKi:  33nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159112(2-(4-Cyclopropyl-piperazin-1-yl)-6-trifluoromethyl...)
Affinity DataKi:  52nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM27213(4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imi...)
Affinity DataKi:  94nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159115(CHEMBL179306 | [2-(4-Cyclopropyl-piperazin-1-yl)-q...)
Affinity DataKi:  110nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159124(5,7-Dichloro-2-(4-cyclopropyl-piperazin-1-yl)-quin...)
Affinity DataKi:  300nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159119(7-Chloro-2-(4-cyclopropyl-piperazin-1-yl)-quinolin...)
Affinity DataKi:  323nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50053631(2-(4-Methyl-piperazin-1-yl)-quinoline | 2-(4-methy...)
Affinity DataKi:  410nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  631nMAssay Description:Antagonist potency against human H3 receptor in GTPgamma[S]-AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159114(CHEMBL179234 | Cyclopropyl-[2-(4-cyclopropyl-piper...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibiton of [3H]-ketanserin binding to human 5-HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159114(CHEMBL179234 | Cyclopropyl-[2-(4-cyclopropyl-piper...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]-pyrilamine binding to human H1 histamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159114(CHEMBL179234 | Cyclopropyl-[2-(4-cyclopropyl-piper...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibiton of [3H]-histamine binding to human H4 histamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159114(CHEMBL179234 | Cyclopropyl-[2-(4-cyclopropyl-piper...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [125I]-aminopotentidine binding to human H2 histamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50159109(2-(4-Cyclopropyl-piperazin-1-yl)-quinoline | CHEMB...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibiton of [3H]-ketanserin binding to human 5-HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed