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Found 19 Enz. Inhib. hit(s) with all data for entry = 50015794
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161080((S)-2-[(S)-3-Isobutyl-2,5-dioxo-4-((E)-3-pyridin-4...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161067((2R)-2-[3-ISOBUTYL-2,5-DIOXO-4-(QUINOLIN-3-YLMETHY...)
Affinity DataIC50:  69nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123241((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161072((S)-2-((S)-3-Isobutyl-2,5-dioxo-4-quinolin-6-yl-[1...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161065((S)-2-((R)-3-Isobutyl-2,5-dioxo-4-quinolin-3-ylmet...)
Affinity DataIC50:  510nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161071((S)-2-[(S)-4-(4-Dimethylamino-benzyl)-3-isobutyl-2...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161076((S)-2-[(S)-3-Isobutyl-4-(3-methyl-quinolin-5-ylmet...)
Affinity DataIC50:  890nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161082((S)-2-[(S)-4-(4-Hydroxy-3-methoxy-benzyl)-3-isobut...)
Affinity DataIC50:  950nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161078((S)-2-[(S)-4-(3-Hydroxy-benzyl)-3-isobutyl-2,5-dio...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161068((S)-2-((S)-4-Benzyl-3-isobutyl-2,5-dioxo-[1,4]diaz...)
Affinity DataIC50:  2.85E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161069((S)-2-[(S)-4-(4-Bromo-benzyl)-3-isobutyl-2,5-dioxo...)
Affinity DataIC50:  2.95E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161075((S)-2-[(S)-4-(4-Bromo-cyclohexa-1,3-dienylmethyl)-...)
Affinity DataIC50:  2.95E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161073((S)-2-[(S)-3-Isobutyl-2,5-dioxo-4-(pyridin-4-ylcar...)
Affinity DataIC50:  3.70E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161070((R)-2-((R)-3-Isobutyl-2,5-dioxo-4-quinolin-3-ylmet...)
Affinity DataIC50:  4.20E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161074((R)-2-((S)-3-Isobutyl-2,5-dioxo-4-quinolin-3-ylmet...)
Affinity DataIC50:  5.70E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161077((S)-2-[(S)-4-(3-Benzyloxy-benzyl)-3-isobutyl-2,5-d...)
Affinity DataIC50:  6.60E+3nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161066((S)-2-[(S)-3-Isobutyl-2,5-dioxo-4-(4-pyridin-3-yl-...)
Affinity DataIC50:  1.33E+4nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161079((S)-2-((S)-3-Isobutyl-2,5-dioxo-4-quinolin-6-ylmet...)
Affinity DataIC50:  2.44E+4nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161081((S)-2-((S)-3-Isobutyl-2,5-dioxo-4-pyridin-4-ylmeth...)
Affinity DataIC50:  3.30E+4nMAssay Description:In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed