Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50015898
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162106(1-Cyclohexyl-2-(2-fluoro-4-hydroxy-phenyl)-1H-benz...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162110(1-Cyclohexyl-2-(4-hydroxy-phenyl)-1H-benzoimidazol...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162109(3-Cyclohexyl-2-(4-hydroxy-phenyl)-1H-indole-6-carb...)
Affinity DataIC50:  4.80nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50158838(2-{4-[2-(4-chlorophenyl)-5-(4-hydroxyhexahydro-1-p...)
Affinity DataIC50: <6nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162099(2-(4-Benzyloxy-phenyl)-3-cyclohexyl-1-dimethylcarb...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162105(3-Cyclohexyl-1-(2-morpholin-4-yl-2-oxo-ethyl)-2-p-...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162104(2-(4-Chloro-phenyl)-3-cyclohexyl-1-dimethylcarbamo...)
Affinity DataIC50:  15nMAssay Description:Inhibitory concentration against NS5B polymerase of Hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162095(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-p-tolyl-1...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162097(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-(4-methox...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162096(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-(3-fluoro...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162108(3-CYCLOHEXYL-1-(2-MORPHOLIN-4-YL-2-OXOETHYL)-2-PHE...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162092(3-Cyclohexyl-1-methyl-2-phenyl-1H-indole-6-carboxy...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162101(1-Benzyl-3-cyclohexyl-2-phenyl-1H-indole-6-carboxy...)
Affinity DataIC50:  37nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162093(2-(3-Chloro-phenyl)-3-cyclohexyl-1-dimethylcarbamo...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162103(3-Cyclohexyl-1-(2-methanesulfonylamino-2-oxo-ethyl...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162094(3-Cyclohexyl-2-phenyl-1H-indole-6-carboxylic acid ...)
Affinity DataIC50:  48nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162102(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-phenyl-1H...)
Affinity DataIC50:  59nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162100(3-Cyclohexyl-1-(2-morpholin-4-yl-ethyl)-2-phenyl-1...)
Affinity DataIC50:  111nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162107(1-Cyclohexyl-2-(4-hydroxy-phenyl)-1H-indole-5-carb...)
Affinity DataIC50:  340nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162111(2-(2-Chloro-phenyl)-3-cyclohexyl-1-dimethylcarbamo...)
Affinity DataIC50:  372nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162098(1-Benzenesulfonyl-3-cyclohexyl-2-phenyl-1H-indole-...)
Affinity DataIC50:  485nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162105(3-Cyclohexyl-1-(2-morpholin-4-yl-2-oxo-ethyl)-2-p-...)
Affinity DataEC50:  300nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162097(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-(4-methox...)
Affinity DataEC50:  0.5nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162093(2-(3-Chloro-phenyl)-3-cyclohexyl-1-dimethylcarbamo...)
Affinity DataEC50:  4.5nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162100(3-Cyclohexyl-1-(2-morpholin-4-yl-ethyl)-2-phenyl-1...)
Affinity DataEC50:  4.60nMAssay Description:Effective concentration for inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162101(1-Benzyl-3-cyclohexyl-2-phenyl-1H-indole-6-carboxy...)
Affinity DataEC50:  14nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162096(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-(3-fluoro...)
Affinity DataEC50:  0.600nMAssay Description:Effective concentration for inhibitory activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162095(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-p-tolyl-1...)
Affinity DataEC50:  0.5nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162094(3-Cyclohexyl-2-phenyl-1H-indole-6-carboxylic acid ...)
Affinity DataEC50:  6.70nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162092(3-Cyclohexyl-1-methyl-2-phenyl-1H-indole-6-carboxy...)
Affinity DataEC50:  6nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162098(1-Benzenesulfonyl-3-cyclohexyl-2-phenyl-1H-indole-...)
Affinity DataEC50: >50nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162104(2-(4-Chloro-phenyl)-3-cyclohexyl-1-dimethylcarbamo...)
Affinity DataEC50:  0.900nMAssay Description:Effective concentration for inhibitory activity against NS5B polymerase of Hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162103(3-Cyclohexyl-1-(2-methanesulfonylamino-2-oxo-ethyl...)
Affinity DataEC50: >50nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162108(3-CYCLOHEXYL-1-(2-MORPHOLIN-4-YL-2-OXOETHYL)-2-PHE...)
Affinity DataEC50:  0.800nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162099(2-(4-Benzyloxy-phenyl)-3-cyclohexyl-1-dimethylcarb...)
Affinity DataEC50:  2.60nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162102(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-phenyl-1H...)
Affinity DataEC50:  1.5nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed