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Found 43 Enz. Inhib. hit(s) with all data for entry = 50037547
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083536(4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...)
Affinity DataKi:  18.7nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carboxylic...)
Affinity DataKi:  21.1nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083528(1-Methyl-4-naphthalen-2-yl-piperidine-4-carbonitri...)
Affinity DataKi:  125nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083536(4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...)
Affinity DataKi:  125nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083532(4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carboxyl...)
Affinity DataKi:  277nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083529(4-(4-Fluoro-phenyl)-1-methyl-piperidine-4-carboxyl...)
Affinity DataKi:  308nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50026752(1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...)
Affinity DataKi:  413nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083531(4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carbonitri...)
Affinity DataKi:  430nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083526(4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...)
Affinity DataKi:  805nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50026752(1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...)
Affinity DataKi:  920nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  1.14E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083525(1-Methyl-4-p-tolyl-piperidine-4-carboxylic acid et...)
Affinity DataKi:  1.61E+3nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  2.03E+3nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083536(4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...)
Affinity DataKi:  2.04E+3nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carboxylic...)
Affinity DataKi:  2.35E+3nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083528(1-Methyl-4-naphthalen-2-yl-piperidine-4-carbonitri...)
Affinity DataKi:  2.36E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083526(4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...)
Affinity DataKi:  2.67E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083525(1-Methyl-4-p-tolyl-piperidine-4-carboxylic acid et...)
Affinity DataKi:  2.67E+3nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carboxylic...)
Affinity DataKi:  3.25E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083532(4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carboxyl...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083532(4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carboxyl...)
Affinity DataKi:  4.41E+3nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083533(4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carbonit...)
Affinity DataKi:  5.11E+3nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083531(4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carbonitri...)
Affinity DataKi:  8.34E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083524(4-(4-Fluoro-phenyl)-1-methyl-piperidine-4-carbonit...)
Affinity DataKi:  1.01E+4nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083529(4-(4-Fluoro-phenyl)-1-methyl-piperidine-4-carboxyl...)
Affinity DataKi:  1.07E+4nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083525(1-Methyl-4-p-tolyl-piperidine-4-carboxylic acid et...)
Affinity DataKi:  1.24E+4nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083527(1-Methyl-4-p-tolyl-piperidine-4-carbonitrile | CHE...)
Affinity DataKi:  1.37E+4nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083528(1-Methyl-4-naphthalen-2-yl-piperidine-4-carbonitri...)
Affinity DataKi:  1.54E+4nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptor at 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083531(4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carbonitri...)
Affinity DataKi:  1.73E+4nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptor at 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50026752(1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...)
Affinity DataKi:  1.78E+4nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083533(4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carbonit...)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083533(4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carbonit...)
Affinity DataKi:  3.68E+4nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptor at 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083526(4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083527(1-Methyl-4-p-tolyl-piperidine-4-carbonitrile | CHE...)
Affinity DataKi:  4.06E+4nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083527(1-Methyl-4-p-tolyl-piperidine-4-carbonitrile | CHE...)
Affinity DataKi:  4.18E+4nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083534(1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...)
Affinity DataKi:  7.11E+4nMAssay Description:Inhibition of [3H]-nisoxetine binding to rat norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083536(4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...)
Affinity DataKi:  7.45E+4nMAssay Description:Inhibition of [3H]-nisoxetine binding to rat norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083524(4-(4-Fluoro-phenyl)-1-methyl-piperidine-4-carbonit...)
Affinity DataKi:  1.01E+5nMAssay Description:Inhibition of [3H]nisoxetine binding to rat norepinephrine transporter at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  3.88E+5nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carboxylic...)
Affinity DataKi:  5.19E+5nMAssay Description:Inhibition of [3H]-nisoxetine binding to rat norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083532(4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carboxyl...)
Affinity DataKi:  6.01E+5nMAssay Description:Inhibition of [3H]-nisoxetine binding to rat norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed