Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 1221
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10215(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-[3-(trifluo...)
Affinity DataKi:  2.70E+3nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10215(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-[3-(trifluo...)
Affinity DataKi:  4.30E+3nM ΔG°:  -30.3kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10215(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-[3-(trifluo...)
Affinity DataKi:  6.20E+3nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10216(BI-7E7 | Burnham Institute Compound 2 | ethyl 2-(2...)
Affinity DataKi:  3.00E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10216(BI-7E7 | Burnham Institute Compound 2 | ethyl 2-(2...)
Affinity DataIC50:  4.00E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10218(BI-9C3 | Burnham Institute Compound 4 | phenyl 2-(...)
Affinity DataIC50:  4.00E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10216(BI-7E7 | Burnham Institute Compound 2 | ethyl 2-(2...)
Affinity DataIC50:  4.60E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10219(BI-9B11 | Burnham Institute Compound 5 | [2-(2,3-d...)
Affinity DataIC50:  5.50E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10218(BI-9C3 | Burnham Institute Compound 4 | phenyl 2-(...)
Affinity DataIC50:  6.00E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10217(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N-(furan-2-yl...)
Affinity DataIC50:  6.00E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10219(BI-9B11 | Burnham Institute Compound 5 | [2-(2,3-d...)
Affinity DataIC50:  6.20E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10222(4-chlorophenyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl...)
Affinity DataIC50:  7.40E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10220(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiazole-...)
Affinity DataIC50:  7.50E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10223(BI-9C5 | Burnham Institute Compound 9 | ethyl 2-(2...)
Affinity DataIC50:  8.20E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10225(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-methyl-1,3-...)
Affinity DataIC50:  1.28E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10221(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N,N-dimethyl-...)
Affinity DataIC50:  1.29E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10217(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N-(furan-2-yl...)
Affinity DataIC50:  1.33E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10224(4-{[2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiaz...)
Affinity DataIC50:  1.50E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10220(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiazole-...)
Affinity DataIC50:  1.70E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10225(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-methyl-1,3-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10224(4-{[2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiaz...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10223(BI-9C5 | Burnham Institute Compound 9 | ethyl 2-(2...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10222(4-chlorophenyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10221(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N,N-dimethyl-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10225(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-methyl-1,3-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10224(4-{[2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiaz...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10223(BI-9C5 | Burnham Institute Compound 9 | ethyl 2-(2...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10222(4-chlorophenyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10219(BI-9B11 | Burnham Institute Compound 5 | [2-(2,3-d...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10218(BI-9C3 | Burnham Institute Compound 4 | phenyl 2-(...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10217(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N-(furan-2-yl...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10220(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiazole-...)
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10221(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N,N-dimethyl-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed