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Found 74 Enz. Inhib. hit(s) with all data for entry = 50016014
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163809(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-oxazol-5-yl-phe...)
Affinity DataIC50:  0.540nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163808(5-Amino-3-(2-ethoxy-ethyl)-3-{4-[4-(1H-pyrazol-4-y...)
Affinity DataIC50:  0.610nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163812(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-fluoro-phenoxy)...)
Affinity DataIC50:  0.870nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163807(5-Amino-3-[4-(4-bromo-phenoxy)-phenoxy]-3-(2-ethox...)
Affinity DataIC50:  0.870nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163824(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-imidazol-1-yl-p...)
Affinity DataIC50:  0.950nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163799(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-[1,3,4]oxadiazo...)
Affinity DataIC50:  1nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163811(5-Amino-3-[4-(4-chloro-phenoxy)-phenoxy]-3-(2-etho...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163796(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-oxazol-2-yl-phe...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163802(5-Amino-3-[4-(biphenyl-4-yloxy)-phenoxy]-3-(2-etho...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163828(5-Butyl-5-[4-(4-fluoro-phenoxy)-phenoxy]-pyrimidin...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163797(5-Amino-3-(2-ethoxy-ethyl)-3-(4-p-tolyloxy-phenoxy...)
Affinity DataIC50:  2.10nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163809(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-oxazol-5-yl-phe...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163810(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(2-fluoro-phenoxy)...)
Affinity DataIC50:  3.10nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163821(5-Amino-3-(2-ethoxy-ethyl)-3-(4-o-tolyloxy-phenoxy...)
Affinity DataIC50:  3.10nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163819(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-thiazol-2-yl-ph...)
Affinity DataIC50:  3.10nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163798(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-pyrrol-1-yl-phe...)
Affinity DataIC50:  3.10nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163814(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-thiazol-4-yl-ph...)
Affinity DataIC50:  3.60nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163803(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-pyrazol-1-yl-ph...)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50410149(CHEMBL2096775)
Affinity DataIC50:  3.90nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163801(5-Amino-3-(2-ethoxy-ethyl)-3-{4-[4-(2H-pyrazol-3-y...)
Affinity DataIC50:  4.10nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163826(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-trifluoromethyl...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163815(4-{4-[5-Amino-3-(2-ethoxy-ethyl)-2,4,6-trioxo-pipe...)
Affinity DataIC50:  5.90nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163817(4-{4-[5-Amino-3-(2-ethoxy-ethyl)-2,4,6-trioxo-pipe...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163813(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-[1,2,4]triazol-...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163827(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(3-fluoro-phenoxy)...)
Affinity DataIC50:  9.20nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163808(5-Amino-3-(2-ethoxy-ethyl)-3-{4-[4-(1H-pyrazol-4-y...)
Affinity DataIC50:  11nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163820(5-Amino-3-{4-[4-(3,4-dihydro-2H-[1,2,4]triazol-3-y...)
Affinity DataIC50:  15nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163810(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(2-fluoro-phenoxy)...)
Affinity DataIC50:  16nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163822(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-oxazol-4-yl-phe...)
Affinity DataIC50:  18nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163811(5-Amino-3-[4-(4-chloro-phenoxy)-phenoxy]-3-(2-etho...)
Affinity DataIC50:  18nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163824(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-imidazol-1-yl-p...)
Affinity DataIC50:  18nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163816(5-Amino-3-(2-ethoxy-ethyl)-3-(4-m-tolyloxy-phenoxy...)
Affinity DataIC50:  19nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163804(4-{4-[5-Amino-3-(2-ethoxy-ethyl)-2,4,6-trioxo-pipe...)
Affinity DataIC50:  19nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163807(5-Amino-3-[4-(4-bromo-phenoxy)-phenoxy]-3-(2-ethox...)
Affinity DataIC50:  19nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163799(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-[1,3,4]oxadiazo...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration against matrix metalloprotease 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163798(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-pyrrol-1-yl-phe...)
Affinity DataIC50:  22nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163797(5-Amino-3-(2-ethoxy-ethyl)-3-(4-p-tolyloxy-phenoxy...)
Affinity DataIC50:  23nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163812(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-fluoro-phenoxy)...)
Affinity DataIC50:  23nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163801(5-Amino-3-(2-ethoxy-ethyl)-3-{4-[4-(2H-pyrazol-3-y...)
Affinity DataIC50:  27nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163805(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-methoxy-phenoxy...)
Affinity DataIC50:  28nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163799(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-[1,3,4]oxadiazo...)
Affinity DataIC50:  29nMAssay Description:Inhibitory concentration against matrix metalloprotease 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163799(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-[1,3,4]oxadiazo...)
Affinity DataIC50:  31nMAssay Description:Inhibitory concentration against matrix metalloprotease 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163802(5-Amino-3-[4-(biphenyl-4-yloxy)-phenoxy]-3-(2-etho...)
Affinity DataIC50:  36nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163816(5-Amino-3-(2-ethoxy-ethyl)-3-(4-m-tolyloxy-phenoxy...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163830(5-Amino-3-[4-(3-chloro-phenoxy)-phenoxy]-3-(2-etho...)
Affinity DataIC50:  53nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163823(4-{4-[5-Amino-3-(2-ethoxy-ethyl)-2,4,6-trioxo-pipe...)
Affinity DataIC50:  56nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163827(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(3-fluoro-phenoxy)...)
Affinity DataIC50:  60nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163821(5-Amino-3-(2-ethoxy-ethyl)-3-(4-o-tolyloxy-phenoxy...)
Affinity DataIC50:  70nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163819(5-Amino-3-(2-ethoxy-ethyl)-3-[4-(4-thiazol-2-yl-ph...)
Affinity DataIC50:  75nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50163830(5-Amino-3-[4-(3-chloro-phenoxy)-phenoxy]-3-(2-etho...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration against matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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