Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 1248
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10403(7-methyl-12-(morpholine-4-sulfonyl)-4-(1,3,5-trime...)
Affinity DataIC50:  4nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10392(7-methyl-4-(2-methylphenyl)-12-(morpholine-4-sulfo...)
Affinity DataIC50:  15nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10385(methyl 2-[7-methyl-12-(morpholine-4-sulfonyl)-3,5-...)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10397(7-methyl-3,5-dioxo-4-(1,3,5-trimethyl-1H-pyrazol-4...)
Affinity DataIC50:  16nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10399(2-hydroxy-N-[7-methyl-3,5-dioxo-4-(1,3,5-trimethyl...)
Affinity DataIC50:  20nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10400(N-(2-methoxyethyl)-7-methyl-3,5-dioxo-4-(1,3,5-tri...)
Affinity DataIC50:  21nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10401(methyl (2S)-2-{[7-methyl-3,5-dioxo-4-(1,3,5-trimet...)
Affinity DataIC50:  23nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10398(7-methyl-3,5-dioxo-4-(1,3,5-trimethyl-1H-pyrazol-4...)
Affinity DataIC50:  33nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10389(methyl 3-[7-methyl-12-(morpholine-4-sulfonyl)-3,5-...)
Affinity DataIC50:  37nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10381(4,7-dimethyl-12-(morpholine-4-sulfonyl)-4,8-diazat...)
Affinity DataIC50:  44nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10402(7-methyl-12-{[(2R)-2-(phenoxymethyl)pyrrolidine-1-...)
Affinity DataIC50:  55nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10395(7-methyl-3,5-dioxo-4-(1,3,5-trimethyl-1H-pyrazol-4...)
Affinity DataIC50:  90nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10393(7-methyl-3,5-dioxo-4-(1,3,5-trimethyl-1H-pyrazol-4...)
Affinity DataIC50:  100nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10393(7-methyl-3,5-dioxo-4-(1,3,5-trimethyl-1H-pyrazol-4...)
Affinity DataIC50:  140nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10378(7-methyl-12-(morpholine-4-sulfonyl)-4,8-diazatricy...)
Affinity DataIC50:  210nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10394(12-bromo-7-methyl-4-(1,3,5-trimethyl-1H-pyrazol-4-...)
Affinity DataIC50:  360nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10384(methyl 2-{12-bromo-7-methyl-3,5-dioxo-4,8-diazatri...)
Affinity DataIC50:  460nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10388(methyl 3-{12-bromo-7-methyl-3,5-dioxo-4,8-diazatri...)
Affinity DataIC50:  1.08E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10380(12-bromo-4,7-dimethyl-4,8-diazatricyclo[7.4.0.0^{2...)
Affinity DataIC50:  1.58E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10383(methyl 2-{12-fluoro-7-methyl-3,5-dioxo-4,8-diazatr...)
Affinity DataIC50:  2.50E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10391(12-bromo-7-methyl-4-(2-methylphenyl)-4,8-diazatric...)
Affinity DataIC50:  2.54E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10382(methyl 2-{7-methyl-3,5-dioxo-4,8-diazatricyclo[7.4...)
Affinity DataIC50:  4.65E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10387(methyl 3-{12-fluoro-7-methyl-3,5-dioxo-4,8-diazatr...)
Affinity DataIC50:  5.50E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10379(4,7-dimethyl-4,8-diazatricyclo[7.4.0.0^{2,6}]tride...)
Affinity DataIC50:  6.36E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10390(7-methyl-4-(2-methylphenyl)-4,8-diazatricyclo[7.4....)
Affinity DataIC50:  8.11E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10386(methyl 3-{7-methyl-3,5-dioxo-4,8-diazatricyclo[7.4...)
Affinity DataIC50:  2.33E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10377(12-bromo-7-methyl-4,8-diazatricyclo[7.4.0.0^{2,6}]...)
Affinity DataIC50:  3.71E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10376(12-fluoro-7-methyl-4,8-diazatricyclo[7.4.0.0^{2,6}...)
Affinity DataIC50:  6.28E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10375(7-methyl-4,8-diazatricyclo[7.4.0.0^{2,6}]trideca-1...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed