Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50016045
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164264((S)-1-(9-Hydroxy-9H-fluorene-9-carbonyl)-pyrrolidi...)
Affinity DataKi:  0.490nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164256((S)-1-(2-Hydroxy-2,2-diphenyl-acetyl)-pyrrolidine-...)
Affinity DataKi:  0.550nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164260((S)-1-(7-Chloro-5-hydroxy-5H-indeno[1,2-b]pyridine...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164260((S)-1-(7-Chloro-5-hydroxy-5H-indeno[1,2-b]pyridine...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164269((S)-1-(5-Hydroxy-5H-indeno[1,2-b]pyridine-5-carbon...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164269((S)-1-(5-Hydroxy-5H-indeno[1,2-b]pyridine-5-carbon...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164268((S)-1-(9-Hydroxy-9H-fluorene-9-carbonyl)-pyrrolidi...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164263((S)-1-(9-Hydroxy-9H-3-aza-fluorene-9-carbonyl)-pyr...)
Affinity DataKi:  2nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164263((S)-1-(9-Hydroxy-9H-3-aza-fluorene-9-carbonyl)-pyr...)
Affinity DataKi:  2nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164266((S)-1-(9-Hydroxy-9H-fluorene-9-carbonyl)-pyrrolidi...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164257((S)-1-(9-Hydroxy-9H-indeno[2,1-c]pyridine-9-carbon...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164257((S)-1-(9-Hydroxy-9H-indeno[2,1-c]pyridine-9-carbon...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164259((S)-1-(9-Hydroxy-9H-indeno[2,1-b]pyridine-9-carbon...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164258((S)-1-(5-Hydroxy-1-oxy-5H-indeno[1,2-b]pyridine-5-...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164259((S)-1-(9-Hydroxy-9H-indeno[2,1-b]pyridine-9-carbon...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164258((S)-1-(5-Hydroxy-1-oxy-5H-indeno[1,2-b]pyridine-5-...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164267((S)-1-(9-Hydroxy-3-oxy-9H-3-aza-fluorene-9-carbony...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164267((S)-1-(9-Hydroxy-3-oxy-9H-3-aza-fluorene-9-carbony...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164262((S)-1-(9-Hydroxy-2-oxy-9H-indeno[2,1-c]pyridine-9-...)
Affinity DataKi:  37nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164262((S)-1-(9-Hydroxy-2-oxy-9H-indeno[2,1-c]pyridine-9-...)
Affinity DataKi:  37nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164265((S)-1-(9-Hydroxy-1-oxy-9H-indeno[2,1-b]pyridine-9-...)
Affinity DataKi:  140nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164265((S)-1-(9-Hydroxy-1-oxy-9H-indeno[2,1-b]pyridine-9-...)
Affinity DataKi:  140nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164260((S)-1-(7-Chloro-5-hydroxy-5H-indeno[1,2-b]pyridine...)
Affinity DataKi:  300nMAssay Description:Inhibitory activity against serine protease trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164261((S)-1-(9-Hydroxy-9H-fluorene-9-carbonyl)-pyrrolidi...)
Affinity DataKi:  550nMAssay Description:Inhibition of coagulation factor II (thrombin) of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164263((S)-1-(9-Hydroxy-9H-3-aza-fluorene-9-carbonyl)-pyr...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibitory activity against kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164263((S)-1-(9-Hydroxy-9H-3-aza-fluorene-9-carbonyl)-pyr...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibitory activity against tissue plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164263((S)-1-(9-Hydroxy-9H-3-aza-fluorene-9-carbonyl)-pyr...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibitory activity against urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164263((S)-1-(9-Hydroxy-9H-3-aza-fluorene-9-carbonyl)-pyr...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed