Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50016164
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM18031(CHEMBL193816 | Ketopiperazine-based inhibitor, 11)
Affinity DataIC50:  7nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165800(7-((S)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phen...)
Affinity DataIC50:  17nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165796((S)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  23nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165802((S)-6-[1-(2-Hydroxy-ethyl)-1,2,3,4-tetrahydro-quin...)
Affinity DataIC50:  33nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165804((S)-6-[1-(3-Hydroxy-propyl)-1,2,3,4-tetrahydro-qui...)
Affinity DataIC50:  35nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM18029((6R)-6-({[1-(3-hydroxypropyl)-1,2,3,4-tetrahydroqu...)
Affinity DataIC50:  37nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM17966((6R)-1-(4-{3-[(2-methoxyphenyl)methoxy]propoxy}phe...)
Affinity DataIC50:  54nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165803((R)-6-[1-(2-Hydroxy-ethyl)-1,2,3,4-tetrahydro-quin...)
Affinity DataIC50:  64nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165798((S)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  66nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165799((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  120nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165797((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  820nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165801((S)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  860nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed