Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 1145
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
University Of Illinois At Chicago

LigandPNGBDBM9264((2R)-2-hydroxy-2-[(10S)-16-hydroxy-12-oxo-3,4,5,6,...)
Affinity DataKi:  0.700nM ΔG°:  -52.3kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
University Of Illinois At Chicago

LigandPNGBDBM9262((2R)-2-hydroxy-2-[(9S)-15-hydroxy-11-oxo-2,3,4,5,6...)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
University Of Illinois At Chicago

LigandPNGBDBM9260((2R)-2-hydroxy-2-[(9S)-15-hydroxy-11-oxo-2,5,6,7,8...)
Affinity DataKi:  2nM ΔG°:  -49.7kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
University Of Illinois At Chicago

LigandPNGBDBM9263(2-(but-3-en-1-yloxy)-3-hydroxy-N-[(2R,3S)-2-hydrox...)
Affinity DataKi:  2nM ΔG°:  -49.7kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
University Of Illinois At Chicago

LigandPNGBDBM9266((2R)-2-hydroxy-2-[(11S)-17-hydroxy-13-oxo-2,3,4,5,...)
Affinity DataKi:  2nM ΔG°:  -49.7kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
University Of Illinois At Chicago

LigandPNGBDBM9268((2R)-N-(2H-1,3-benzodioxol-5-yl)-2-hydroxy-2-[(10S...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
University Of Illinois At Chicago

LigandPNGBDBM9265(3-hydroxy-N-[(1S)-1-((1R)-1-hydroxy-2-{isobutyl[(4...)
Affinity DataKi:  9nM ΔG°:  -45.9kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
University Of Illinois At Chicago

LigandPNGBDBM9259(2-(allyloxy)-3-hydroxy-N-[(1S)-1-((1R)-1-hydroxy-2...)
Affinity DataKi:  12nM ΔG°:  -45.2kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
University Of Illinois At Chicago

LigandPNGBDBM9267(N-((1S)-1-{(1R)-2-[(1,3-benzodioxol-5-ylsulfonyl)(...)
Affinity DataKi:  20nM ΔG°:  -43.9kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
University Of Illinois At Chicago

LigandPNGBDBM9261(2,3-dihydroxy-N-[(1S)-1-((1R)-1-hydroxy-2-{isobuty...)
Affinity DataKi:  270nM ΔG°:  -37.5kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed