Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 2921
LigandPNGBDBM26078(2-(carbamoylamino)-5-{2-[5-(hydroxymethyl)thiophen...)
Affinity DataIC50:  195nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26087(2-(carbamoylamino)-5-(2-cyclopropylethynyl)thiophe...)
Affinity DataIC50:  273nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26086(2-(carbamoylamino)-5-[2-(3-hydroxyphenyl)ethynyl]t...)
Affinity DataIC50:  303nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26082(2-(carbamoylamino)-5-[2-(3-fluorophenyl)ethynyl]th...)
Affinity DataIC50:  331nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26081(2-(carbamoylamino)-5-[2-(5-cyanothiophen-3-yl)ethy...)
Affinity DataIC50:  333nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26077(2-(carbamoylamino)-5-[2-(thiophen-3-yl)ethynyl]thi...)
Affinity DataIC50:  420nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26097(2-(carbamoylamino)-5-[2-(3-methanesulfonamidopheny...)
Affinity DataIC50:  454nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26079(2-(carbamoylamino)-5-{2-[5-(1-hydroxypropyl)thioph...)
Affinity DataIC50:  465nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26090(5-acetylenyl-3-thiophenecarboxamide, 1n | N-(3-{2-...)
Affinity DataIC50:  557nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26080(2-(carbamoylamino)-5-{2-[5-(1-hydroxy-2-methylprop...)
Affinity DataIC50:  563nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26083(2-(carbamoylamino)-5-[2-(2-fluorophenyl)ethynyl]th...)
Affinity DataIC50:  620nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26092(5-[2-(3-benzamidophenyl)ethynyl]-2-(carbamoylamino...)
Affinity DataIC50:  704nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26088(5-[2-(3-aminophenyl)ethynyl]-2-(carbamoylamino)thi...)
Affinity DataIC50:  709nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26085(2-(carbamoylamino)-5-[2-(2-methylphenyl)ethynyl]th...)
Affinity DataIC50:  716nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26093(2-(carbamoylamino)-5-[2-(3-acetamidophenyl)ethynyl...)
Affinity DataIC50:  964nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26094(2-(carbamoylamino)-5-{2-[3-(2,2,2-trifluoroacetami...)
Affinity DataIC50:  980nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26084(2-(carbamoylamino)-5-[2-(2-chlorophenyl)ethynyl]th...)
Affinity DataIC50:  1.01E+3nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26091(5-acetylenyl-3-thiophenecarboxamide, 1o | N-(3-{2-...)
Affinity DataIC50:  1.85E+3nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26095(2-(carbamoylamino)-5-(2-{3-[2-(dimethylamino)aceta...)
Affinity DataIC50:  1.88E+3nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26096(5-acetylenyl-3-thiophenecarboxamide, 1t | methyl N...)
Affinity DataIC50:  4.40E+3nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26098(3-amino-5-(thiophen-3-yl)thiophene-2-carboxamide |...)
Affinity DataIC50:  1.12E+4nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM26089(5-acetylenyl-3-thiophenecarboxamide, 1m | N-(3-{2-...)
Affinity DataIC50: >2.00E+4nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed