Affinity DataKi: 0.370nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D4.4 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards porcine serotonin receptor 5-HT1A using [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D4.4 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D4.4 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D4.4 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D3 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D4.4 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D3 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D3 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D4.4 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D3 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D3 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D3 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Binding affinity towards porcine serotonin receptor 5-HT1A using [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 short expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Binding affinity towards porcine serotonin receptor 5-HT1A using [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 short expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity towards porcine serotonin receptor 5-HT1A using [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D3 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D4.4 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Binding affinity towards porcine serotonin receptor 5-HT1A using [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 long expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 long expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D4.4 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 short expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 short expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D3 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 66nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 long expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 short expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataKi: 77nMAssay Description:Binding affinity towards porcine serotonin receptor 5-HT1A using [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 short expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataKi: 81nMAssay Description:Binding affinity towards porcine serotonin receptor 5-HT1A using [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 99nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 long expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 long expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 short expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 long expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 long expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 shortMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Binding affinity towards porcine serotonin receptor 5-HT1A using [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 long expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 330nMAssay Description:Inhibition of [3H]-SCH- 23390 binding to dopamine receptor D1 of porcine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 630nMAssay Description:Inhibition of [3H]-SCH- 23390 binding to dopamine receptor D1 of porcine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 720nMAssay Description:Inhibition of [3H]-SCH- 23390 binding to dopamine receptor D1 of porcine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 750nMAssay Description:Inhibition of [3H]-SCH- 23390 binding to dopamine receptor D1 of porcine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 760nMAssay Description:Inhibition of [3H]-SCH- 23390 binding to dopamine receptor D1 of porcine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of [3H]-SCH- 23390 binding to dopamine receptor D1 of porcine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of [3H]-SCH- 23390 binding to dopamine receptor D1 of porcine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Inhibition of [3H]-SCH- 23390 binding to dopamine receptor D1 of porcine striatal membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 7.60nMAssay Description:Effective concentration from [3H]thymidine uptake assay in CHO10001 cells expressing human Dopamine receptor D4.2More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Effective concentration in [3H]thymidine uptake assay by CHO dhfr- mutant cells expressing human D3 receptorMore data for this Ligand-Target Pair