Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with all data for entry = 50016486
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  48nMAssay Description:Inhibitory concentration against p38 alpha MAP kinase (Experimental value)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  72nMAssay Description:Inhibitory concentration against p38 alpha MAP kinase calculated by CoMFA model; FlexX score=-22.2kcal/mol More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50072064(5-Chloro-3-(4-methanesulfonyl-phenyl)-6''-methyl-[...)
Affinity DataIC50:  530nMAssay Description:Inhibitory concentration against p38 alpha MAP kinase calculated by CoMFA model; FlexX score=-18.6kcal/mol More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  810nMAssay Description:Inhibitory concentration against p38 alpha MAP kinase calculated by CoMFA model; FlexX score=-12.4 kcal/molMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed