Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50016518
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169942(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[2-(4-methanesu...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169930(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[(cyclopropylme...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169899(3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against hepatitis C virus NS5B polymerase enzyme; Range=6-9 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169911(3-Cyclohexyl-1-[2-(2-diethylaminomethyl-morpholin-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against hepatitis C virus NS5B polymerase enzyme; Range=6-9 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169906(3-Cyclohexyl-1-[2-(2-diethylaminomethyl-morpholin-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against hepatitis C virus NS5B polymerase enzyme; Range=6-9 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169922(3-Cyclohexyl-1-[2-(4-diethylamino-piperidin-1-yl)-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against hepatitis C virus NS5B polymerase enzyme; Range=6-9 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169904(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[2-(4-diethylam...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against hepatitis C virus NS5B polymerase enzyme; Range=6-9 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169903(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[(isopropyl-met...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169915(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[2-(1,1-dioxo-1...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169920(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[2-(4-methyl-pi...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169931(2-(4-Chloro-phenyl)-3-cyclohexyl-1-{[methyl-(1-met...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169919(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[2-(4-dimethyla...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169932(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[(dimethylcarba...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169929(2-Cyclohex-1-enyl-3-cyclohexyl-1-[2-(4-dimethylami...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169921(3-Cyclohexyl-2-[3-(3,3-difluoro-piperidin-1-ylmeth...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169916(3-Cyclohexyl-1-{[methyl-(1-methyl-piperidin-3-ylme...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169910(3-Cyclohexyl-1-[2-(4-methanesulfonyl-piperazin-1-y...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169927(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-furan-3-y...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169933(3-Cyclohexyl-1-[2-(4-methyl-piperazin-1-yl)-2-oxo-...)
Affinity DataIC50:  39nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169898(3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)...)
Affinity DataIC50:  41nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169907(3-Cyclohexyl-1-[2-(1,1-dioxo-1lambda*6*-thiomorpho...)
Affinity DataIC50:  43nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169938(3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)...)
Affinity DataIC50:  47nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169908(3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)...)
Affinity DataIC50:  49nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162102(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-phenyl-1H...)
Affinity DataIC50:  59nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169946(3-Cyclohexyl-1-[(isopropyl-methyl-carbamoyl)-methy...)
Affinity DataIC50:  62nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169924(3-Cyclohexyl-1-[(cyclopropylmethyl-carbamoyl)-meth...)
Affinity DataIC50:  63nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169928(3-Cyclopentyl-1-[2-(4-methyl-piperazin-1-yl)-2-oxo...)
Affinity DataIC50:  68nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169917(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-(6-methox...)
Affinity DataIC50:  69nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169918(3-Cyclohexyl-1-[2-(4-dimethylamino-pyrrolidin-2-yl...)
Affinity DataIC50:  71nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169912(2,3-Dicyclohexyl-1-[2-(4-dimethylamino-piperidin-1...)
Affinity DataIC50:  72nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169900(2-(4-Chloro-3-dimethylaminomethyl-phenyl)-3-cycloh...)
Affinity DataIC50:  78nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169905(3-Cyclopentyl-1-[2-(4-dimethylamino-pyrrolidin-2-y...)
Affinity DataIC50:  78nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169913(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-{3-[(isop...)
Affinity DataIC50:  78nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169901(3-Cyclohexyl-1-[(dimethylcarbamoylmethyl-methyl-ca...)
Affinity DataIC50:  98nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169923(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-pyridin-4...)
Affinity DataIC50:  134nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169925(3-Cyclohexyl-2-(3-dimethylaminomethyl-phenyl)-1-di...)
Affinity DataIC50:  147nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169909(3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)...)
Affinity DataIC50:  228nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169943(3-Cyclohexyl-1-[2-(4-dimethylamino-pyrrolidin-2-yl...)
Affinity DataIC50:  244nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169940(3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)...)
Affinity DataIC50:  283nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169914(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-pyridin-3...)
Affinity DataIC50:  332nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169937(3-Cyclohexyl-1-[2-(4-methyl-piperazin-1-yl)-2-oxo-...)
Affinity DataIC50:  448nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169902(3-Cyclohexyl-2-(4-dimethylaminomethyl-phenyl)-1-di...)
Affinity DataIC50:  920nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed